13 - Viral Hepatitis

a. Picornavirus

[Hepatitis Virus]

The virus family of Hepatitis A
a. Picornavirus
b. Hepadnavirus
c. Flavivirus
d. Deltavirus

a. Fecal-oral

[Hepatitis Virus]

The route of transmission for Hepatitis A
a. Fecal-oral
b. Sexual
c. Parenteral
d. Vertical

b. Acute only

[Hepatitis Virus]

Clinical course of Hepatitis A virus infection
a. Chronic
b. Acute only
c. Acute → recovery
d. Co-infection

b. GIT symptoms

[Hepatitis Virus]

Initial clinical presentation of Hepatitis A
a. Jaundice
b. GIT symptoms
c. Cirrhosis
d. Liver cancer

b. Without symptoms

[Hepatitis Virus]

Clinical presentation of Hepatitis A in children
a. With symptoms
b. Without symptoms
c. Jaundice
d. Liver cancer

b. HAV-IgM

[Hepatitis Virus]

Diagnostic marker for acute Hepatitis A infection
a. HAV-IgG
b. HAV-IgM
c. HBsAg
d. HCV-RNA

b. HAV-IgG

[Hepatitis Virus]

Diagnostic marker for past Hepatitis A infection
a. HAV-IgM
b. HAV-IgG
c. HBsAg
d. HCV-RNA

c. Supportive

[Hepatitis Virus]

What to do (WTD) for Hepatitis A infection
a. RT inhibitor
b. Interferon
c. Supportive
d. Liver transplant

b. Ig vaccine

[Hepatitis Virus]

Prevention for Hepatitis A
a. Interferon
b. Ig vaccine
c. Ribavirin
d. Liver transplant

c. Hepadnavirus

[Hepatitis Virus]

Viral family classification of Hepatitis B virus
a. Picornavirus
b. Flavivirus
c. Hepadnavirus
d. Hepevirus

a. Dane particle

[Hepatitis Virus]

Form of the virus in Hepatitis B that is:

• Intact

• Complete virus with reverse transciptase

a. Dane particle
b. Spherical particle
c. Tubular particle
d. Filamentous particle

c. Reverse transcriptase

[Hepatitis Virus]

Enzyme present in the Dane particle of Hepatitis B
a. RNA polymerase
b. DNA polymerase
c. Reverse transcriptase
d. Ligase

• Sexual

• Vertical

• Parenteral

[Hepatitis Virus]

Route of transmission of Hepatitis B
a. Fecal-oral
b. Parenteral via BT
c. Sexual, vertical, parenteral
d. Fecal-oral "TAE"

b. 6 months

[Hepatitis Virus]

Clinical course of Hepatitis B that progresses to recovery within how many months
a. 3 months
b. 6 months
c. 9 months
d. 12 months

• Cirrhosis

• Liver cancer

[Hepatitis Virus]

Complication (WOF) of chronic Hepatitis B
a. Renal failure
b. Cirrhosis, liver cancer
c. Peripheral neuropathy
d. Aplastic anemia

b. Hepatitis B profile

[Hepatitis Virus]

Diagnostic test for Hepatitis B
a. HAV-IgM
b. Hepatitis B profile
c. HCV-RNA genotyping
d. HEV-IgM

b. RT inhibitor

• Tenofovir

• Entacavir

[Hepatitis Virus]

Treatment class used for Hepatitis B
a. Interferon
b. RT inhibitor
c. Ribavirin
d. Supportive only

• Tenofovir

• Entacavir

[Hepatitis Virus]

RT inhibitor drug used for Hepatitis B
a. Tenofovir and Entecavir
b. Interferon and Ribavirin
c. Lamivudine and Adefovir
d. Telaprevir and Boceprevir

b. Ig vaccine

[Hepatitis Virus]

Prevention for Hepatitis B
a. Interferon
b. Ig vaccine
c. Ribavirin
d. Liver transplant

b. Flavivirus

[Hepatitis Virus]

Viral family classification of Hepatitis C virus
a. Picornavirus
b. Flavivirus
c. Hepadnavirus
d. Hepevirus

• Parenteral

  • via BT

  • IV drug users

[Hepatitis Virus]

Route of transmission of Hepatitis C
a. Fecal-oral
b. Sexual, vertical
c. Parenteral
d. Fecal-oral "TAE"

b. Chronic

[Hepatitis Virus]

Clinical course of Hepatitis C infection
a. Acute only
b. Chronic
c. Co-infection
d. Superinfection

b. No immunity

[Hepatitis Virus]

Immunity status after Hepatitis C infection
a. Lifelong immunity
b. No immunity
c. Partial immunity
d. Temporary immunity

c. HCV-RNA genotyping

[Hepatitis Virus]

Diagnostic test for Hepatitis C
a. HAV-IgM
b. Hepatitis B profile
c. HCV-RNA genotyping
d. HEV-IgM

• Interferon

• Ribavirin

• Liver transplant

[Hepatitis Virus]

Treatment for Hepatitis C

a. Interferon, Ribavirin, Liver transplant
b. Tenofovir, Entecavir, Liver transplant
c. Interferon, Ribavirin, Supportive therapy
d. Ig, Vaccine, Liver transplant

c. No prevention/vaccine

[Hepatitis Virus]

Prevention for Hepatitis C

a. Ig vaccine

b. Vaccine available

c. No prevention/vaccine

d. RT inhibitor

d. Deltavirus

[Hepatitis Virus]

Viral family classification of Hepatitis D virus
a. Picornavirus
b. Flavivirus
c. Hepadnavirus
d. Deltavirus

• Sexual

• Vertical

• Parenteral

[Hepatitis Virus]

Route of transmission of Hepatitis D which is same as Hepatitis B
a. Fecal-oral
b. Sexual, Vertical, Parenteral
c. Fecal-oral
d. Parenteral via BT only

b. Co-infection

[Hepatitis Virus]

Clinical condition when a patient is infected with both HBV and HDV simultaneously
a. Superinfection
b. Co-infection
c. Chronic infection
d. Reinfection

b. Superinfection

[Hepatitis Virus]

Clinical condition when HBV infection is followed by HDV infection
a. Co-infection
b. Superinfection
c. Chronic infection
d. Reinfection

b. RT inhibitor

• Tenofovir

• Entacavir

[Hepatitis Virus]

Treatment for Hepatitis D infection
a. Interferon
b. RT inhibitor
c. Ribavirin
d. Supportive only

b. Ig vaccine

[Hepatitis Virus]

Prevention for Hepatitis D infection
a. Interferon
b. Ig vaccine
c. Ribavirin
d. Liver transplant

d. Hepevirus

[Hepatitis Virus]

Viral family classification of Hepatitis E virus
a. Picornavirus
b. Flavivirus
c. Hepadnavirus
d. Hepevirus

c. Fecal-oral

📌CLUE: “tAE”

• Hepatitis A

• Hepatitis E

[Hepatitis Virus]

Route of transmission of Hepatitis E

a. Sexual, vertical, parenteral
b. Parenteral via BT
c. Fecal-oral
d. Same as Hepatitis B

b. Acute only

[Hepatitis Virus]

Clinical course of Hepatitis E infection
a. Chronic
b. Acute only
c. Co-infection
d. Superinfection

c. Pregnant

[Hepatitis Virus]

Population with increased mortality from Hepatitis E infection

a. Elderly
b. Children
c. Pregnant
d. Immunocompromised

a. Hepatitis E

[Hepatitis Virus]

Associated with contaminated beverages
a. Hepatitis E
b. Hepatitis A
c. Hepatitis B
d. Hepatitis C

d. HEV-IgM

[Hepatitis Virus]

Diagnostic marker for Hepatitis E
a. HAV-IgM
b. Hepatitis B profile
c. HCV-RNA genotyping
d. HEV-IgM

c. Supportive

[Hepatitis Virus]

Treatment for Hepatitis E infection
a. RT inhibitor
b. Interferon
c. Supportive
d. Ribavirin

c. Vaccine (uncertain/not established)

[Hepatitis Virus]

Prevention for Hepatitis E infection
a. Ig vaccine
b. RT inhibitor
c. Vaccine (uncertain/not established)
d. Ribavirin

c. HBsAg

[Marker]

• General marker of Hepatitis B infection

• known as "surface”

a. HBcAg
b. Anti-HBs
c. HBsAg
d. HBeAg

b. HBeAg

[Marker]

Reactive if the patient has been vaccinated against Hepatitis B
a. HBsAg
b. HBeAg
c. Anti-HBs
d. HBcAg

d. Anti-HBs

[Marker]

Indicates immunity or recovery to Hepatitis B virus
a. HBsAg
b. HBeAg
c. HBcAg
d. Anti-HBs

b. HBcAg

[Marker]

• Indicates actual infection

• known as "core"
  

a. HBsAg
b. HBcAg
c. HBeAg
d. Anti-HBs

b. Anti HBc IgM

[Marker]

Used to ascertain that the patient has an acute Hepatitis B infection
a. Anti HBc IgG
b. Anti HBc IgM
c. Anti-HBs
d. HBeAg

c. Anti HBc IgG

[Marker]

Used to ascertain that the patient has an old/chronic Hepatitis B infection
a. Anti HBc IgM
b. Anti-HBs
c. Anti HBc IgG
d. HBeAg

b. HBeAg

[Marker]

• Indicates high infectivity and active disease of Hepatitis B

• known as "envelope"
  

a. HBsAg
b. HBeAg
c. HBcAg
d. Anti-HBs

b. Anti HBeAg

[Marker]

Indicates low infectivity and virus is no longer replicating in Hepatitis B
a. HBeAg
b. Anti HBeAg
c. HBsAg
d. Anti HBc IgM