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Where is carnosine found?
animal products
What are the actions of carnosine?
buffer (keep body at normal pH)
antioxidant
glycation inhibition
increases Ca2+ sensitivity (more forceful/easier contraction)
What factors effect muscle carnosine levels?
fiber type
sex
age
diet
training status
What type of muscle fibers have higher levels of carnosine, Type 1 or 2?
type 2
Do males or females have higher carnosine levels?
males
What happens to carnosine levels as you age?
decrease
Supplementation of ___ can help increase carnosine
beta alanine
Beta alanine is endogenously produced via ___ in the ___
uracil degradation via the liver
What dose of beta alanine gains benefits?
3.2 g/day increased carnosine by 40%
recommended to spread doses out throughout day
What dose of beta alanine causes paresthesia (tingling)?
greater than 10 mg/kg body weight
800 mg
What is the ergogenic benefit of beta alanine supplementation?
Buffer: prevents muscle getting too acidic, reduces fatigue
increase work capacity
total work
delay neuromuscular fatigue
How does beta alanine impact Vo2 and strength?
current literature suggest no or minimal impact on Vo2 and strength performance
What type of exercise are the benefits seen?
high intensity short duration
What are the adverse effects of beta alanine?
paresthesia
what is the recommended dose of beta alanine?
4-6g/day
What does beet root juice do?
enhances nitric oxide (NO) bioavailability because beet root is nitrate rich
What are the performance benefits of beet root jutice?
reduce O2 cost of exercise
improved blood flow (vasodilation), increase o2 delivery to muscle
improved exercise economy, use less oxygen, don’t have to work as hard
improve muscle contractility
improve BP
do more reps
dosing of beet root
0.5 liters or equivalent high nitrate foodstuff