farma 2

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10 Terms

1
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Vancomycin

Inhibits bacterial cell wall synthesis by binding to D-alanyl-D-alanine terminal

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Metronidazole

Generates free radicals damaging the DNA

3
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Penicilin

Inhibits bacterial cell wall synthesis by binding to PBSs causing bacterial lysis

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Cephalosporin 3G

Prevents bacteria from building their cell wall. They block penicillin-binding proteins that help form the cell wall, causing the bacteria to burst and die

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Daptomycin

Binds to the bacterial cell membrane and creates tiny holes in it, causing ions

(Calcium and Potassium) to leak out, which disrupts the cell’s internal balance

and leads to bacterial death

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Statins

Blocks an enzyme in the liver called HMG-CoA reductase, which the body uses

to make cholesterol, so they lower the amount of cholesterol in the blood,

especially LDL (bad cholesterol)

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Doxycycline

Binds to 30s ribosomal subunits, preventing tRNA bindings, and

bacterial protein synthesis

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Chloramphenicol

Binds to 50s ribosomal subunits, peptidyl transferase

enzyme, preventing amino acids from being added to the growing protein chain.

Preventing bacteria from producing certain protein that helps it survive

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Piperacilin

Inhibits bacterial cell wall synthesis by binding to penicillin-binding

proteins (PRPs)

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Tazobactam

B-lactamase inhibitor preventing degradation of piperacillin

B-lactamase