Module 2 tuts glycolysis

3 PARTS OF GLYCOLYSIS

PART 1: Preparatory Phase or Investment Phase

• Glucose is being prepared for oxidation

PART 2: Cleavage

• The 6C molecule splits up forming 2, 3-carbon fragments

PART 3: Oxidative Phase

• Glyceraldehyde-3-Phosphate is oxidized to generate energy for the cell

_________________One glucose molecule generates 2 molecules of pyruvate and 2 units of ATP

End product: Pyruvate

The first part is Preparatory Phase (works on the six-carbon molecule, preparing it for oxidation)

The second part is the splitting of the 6-carbon molecule into _________________fragments

(GLUCOSE → Glyceraldehyde-3-phosphate and Dihydroxyacetone phosphate)

The third part operates on one of the glyceraldehyde 3-phosphare molecules, oxidizing it to yield energy

PART 1: PREPARATORY PHASE

Step 1

• Glucose to Glucose-6-Phosphate

• Enzyme:

• Reaction:

PART 1: PREPARATORY PHASE

Step 2

• Glucose-6-Phosphate to Fructose-6-Phosphate

• Enzyme:

• Reaction:

PART 1: PREPARATORY PHASE

Step 3

• Fructose-6-Phosphate to Fructose-1,6-Bisphosphate

• Enzyme:

• Reaction:

PART 2: CLEAVAGE

Step 4

• Fructose-1,6-bisphosphate to Glyceraldehyde-3-phosphate and Dihydroxyacetone-phosphate

• Enzyme:

• Reaction:

PART 2: CLEAVAGE

Step 5

• Dihydroxyacetone-phosphate to Glyceraldehyde-3-phosphate

• Enzyme:

• Reaction:

PART 3: OXIDATIVE PHASE

Step 6

• Glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

• Enzyme:

• Reaction:

PART 3: OXIDATIVE PHASE

Step 7

• 1,3-bisphosphoglycerate to 3-phosphoglycerate

• Enzyme:

• Reaction:

PART 3: OXIDATIVE PHASE

Step 8

• 3-phosphoglycerate to 2-phosphpglycerate

• Enzyme:

• Reaction:

PART 3: OXIDATIVE PHASE

Step 9

• 2-phosphoglycerate to phosphoenolpyruvate

• Enzyme:

• Reaction:

PART 3: OXIDATIVE PHASE

Step 10

• Phosphoenolpyruvate to pyruvate

• Enzyme:

• Reaction: