WK 5 Anxiety and Insomnia

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14 Terms

1
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benzo indications

  • at lower dosage → reduce anxiety

  • at high dose → produce sedation and sleep

  • anticonvulsants

  • anesthetics

2
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anxiety disorders

  • GAD

  • OCD

  • Panic disorder

  • PTSD

  • social anxiety

3
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benzo meds

•Diazepam (Valium)

•Alprazolam (Xanax)

•Clorazepate (Tranzene)

•Lorazepam (Ativan)

•Midazolam (Versed)

•Temazepam (Restoril)

•Clonazepam (Klonopin)

•Chlordiazepoxide (Librium)

•Flurazepam (Dalmane)

•Triazolam (Halcion)

•Oxazepam

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benzodiazepine

  • SCHEDULE IV → may physiologic dependence

  • DO NOT discontinue abruptly

    • may have additive effects w/ CNS depressants

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benzo effects

  • dizzy, drowsy, confusion, resp. Depression, visual disturb, nausea, constipation, dry mouth

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benzo contraindications

COPD, sleep apnea, renal and hepatic failure, pregnancy and lactation

  • ETOH and substance abuse

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flumazenil

reversal agent for overdose of benznodiazpene

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Lunesta

eszopiclone

  • SCHEULE IV

  • used for CHRONIC INSOMNIA

  • may cause behavioral changes/memory

  • DO NOT take with high fat meals, grapefruit juice, CYP-450 meds or other CNS depressants

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Sonata

Zaleplon

  • SCHEDULE IV

  • used for SHORT TERM INSOMNIA

  • may cause depression, dizzy, drowsy, amnesia

  • DO NOT take with high fat meals, cimetidine, or other CNS depress

  • DOES NOT interact with CYP 450 meds

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Ambien

Zolpidem

  • SCHEUDLE IV

  • used for SHORT TERM INSOMIA→ cause rebound insomnia, withdrawal symptoms

  • DO NOT take with other CNS depressants

11
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rozerem

ramelteon

  • NOT A CONTROLLED SUBSTANCE

  • works on melatonin receptors

  • used for LONG TERM INSOMNIA

  • may cause dizzy, joint pain, altered taste

  • DO NOT take with high fat meals or other CNS

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Kava

herbal

  • used to treat anxiety and insomnia

  • may lead to liver failure if taken with ETOH

  • may cause pulm. hypertension and decreased platelets and lymphocytes

  • interacts with other CNS depress. anti platelet meds and parkinson’s meds

    • SHOULD NOT be used by pregnant. lactating and children under age of 12

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melatonin

used for insomnia

  • contraindication in CV disease and neurological disorders

  • may interact with other CNS depress.

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valerian

used for insomnia

  • SHOUDL NOT be used in hepatic failure, pregnancy and lactation

  • may interact with other CNS depress