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infection
invasion or colonization of the body by a pathogen
disease
any change from a state of health
acute
type of disease that develops rapidly but is short term
chronic
type of disease that develops slowly but has a continual progression
latent
type of disease where a pathogen remains inactive until conditions are right for its activation
communicable
type of disease that spreads from host to host
contagious
type of communicable disease that easily spreads from host to host
non-communicable
type of disease that is not spread from host to host
epidemiology
study of where and when diseases occur
incidence
number of new cases of a disease in a given population or area
Prevalence
total number of cases of a disease in a given population or area
endemic
a disease that occurs at a relatively stable frequency in a given population or area
epidemic
a disease that occurs at a greater frequency in a given population or area
pandemic
an epidemic disease that occurs simultaneously on more than one continent
sporadic
a disease that there are only a few cases of at any given time
etiology
the cause of an infectious disease
sign
an objective manifestation of a disease
symptom
a subjective manifestation of a disease
pathogenicity
the ability to cause a disease
virulence
the degree of pathogenicity of a disease
symbiosis
two organisms living together
mutualism
two organisms living together where both benefit from the relationship
commensalism
two organisms living together where one benefits and the other is unaffected
parasitism
two organisms living together where one benefits and the other is harmed
biofilm
slimy glue like substance bacteria secrete to help them adhere to surfaces in aqueous environments
extra-cellular enzymes, toxins, anti-phagocytic factors
What are the 3 virulence factors
No
Do antibiotics stop extra-cellular enzymes
cytotoxin
Type of toxin that kills or affects the function of a cell
neurotoxin
Type of toxin that interferes with nerve fibers
enterotoxin
type of toxin that kills the cells lining the GI tract
animal, human and non-living
what are the 3 reservoirs of infectious disease
respiratory tract
What is the most common portal of entry
broken skin, mucous membranes, placenta, parenteral
what are the 4 portals of entry through which pathogens can invade
parenteral
portal of entry in which the pathogen is directly deposited into the tissue by something like a needle stick or mosquito bite
the same way they came in, but via secretions
How do pathogens typically exit a human host
Incubation, vague/general signs and symptoms, illness, decline, convalescence
what are the five stages of infectious disease
contact, vehicle, vector
What are the three modes of transmission of infectious diseases
direct contact
person to person disease transfer through bodily contact
indirect contact
person to person disease transfer via a fomite
direct, indirect, droplet
what are the 3 types of contact transmission of infectious disease
vehicle transmission
what type of infectious disease transmission is spread by air, water, fluid and body fluids
vector
what type of infectious disease transmission is spread by insects that are either infected with or passively carrying the disease
catheter-associated urinary tract infection
what is the most common healthcare acquired infection
wash your hands, maintain good housekeeping, use PPE correctly, handle sharps promptly, isolate patients with infectious disease, prescribe antibiotics appropriately, educate staff/patients/visitors
what are some ways we can decrease the risk of getting a healthcare acquired infection