F&E Chest Pain 5

Thrombolytic Therapy Indication

If cannot receive PCI within 120 min.

Thrombolytic Therapy Timing Target

Door to needle time <= 30 min.

Thrombolytic Therapy Best Outcomes Window

3 - 6 hours.

Thrombolytic Therapy Examples

alteplase, streptokinase, urokinase.

Thrombolytic Therapy Success Criteria

enhance ST elevation & chest pain by 50%.

Aortic Dissection Pathophysiology

anterograde or retrograde flow of blood within the outer third of the tunica media.

Aortic Dissection Stanford Type A Location

ascending aorta and/or the arch of aorta.

Aortic Dissection Stanford Type B Location

descending aorta.

Aortic Dissection DeBakey Type I Location

entire aorta.

Aortic Dissection DeBakey Type II Location

ascending / arch of aorta.

Aortic Dissection DeBakey Type III Location

descending aorta.

Aortic Dissection Predisposing Factors - Common Condition

Hypertension.

Aortic Dissection Predisposing Factors - Syndromes and States

Turners Syndrome, Pregnancy.

Aortic Dissection Predisposing Factors - Congenital Anomalies

Bicuspid aortic valve, Coarctation of the aorta.

Aortic Dissection Rupture - Ascending aorta consequences

Hemopericardium, Right hemothorax.

Aortic Dissection Rupture - Arch of aorta consequence

Compression of pulmonary trunk.

Aortic Dissection Occlusion - Coronary artery consequence

ST elevation myocardial infarction.

Aortic Dissection Occlusion - Subclavian artery consequence

An acutely ischemic upper limb.

Aortic Dissection Occlusion - Coeliac/mesenteric artery consequence

Ischemic bowel.

Aortic Dissection Occlusion - Renal artery consequence

Frank hematuria.

Aortic Dissection Occlusion - Spinal artery consequence

Sudden onset painless paraplegia.

Aortic Dissection Complications - Acute aortic regurgitation signs

Diastolic murmur, Hemopericardium.