Top 300 Quiz 3

KETOCONAZOLE TOPICAL

generic

Nizoral

Ketodan

KETOCONAZOLE TOPICAL

Dosage Forms

Topical Cream

Topical Foam

Topical Gel

Topical Shampoo

KETOCONAZOLE TOPICAL

Topical Cream

Topical Foam

Topical Gel

2%

KETOCONAZOLE TOPICAL

Topical Shampoo

1%

OTC: 2%

KETOCONAZOLE TOPICAL

Common FDA Label Indication, Dosing, and Titration

Candidiasis of skin

Dandruff

Pityriasis versicolor

Seborrheic dermatitis

Tinea corporis

Tinea cruris

Tinea pedis

KETOCONAZOLE TOPICAL

Contraindications

avoid areas that are broken or inflamed on scalp

KETOCONAZOLE TOPICAL

Adverse Reactions

Application site reaction with foam

Rash, hair loss, hypersensitivity

KETOCONAZOLE TOPICAL

Key Patient Counseling Points

Apply a thin layer to affected area of skin

Do not get it in your eyes, nose, mouth, or vagina

Do not wash the areas where you applied this medicine for at least 3 h after application

Cosmetics may be put on the affected areas 20 min after application

Topical products are alcohol-based and flammable immediately after application.

ALTEPLASE

generic

Activase

Cathflo Activase

ALTEPLASE

Dosage Forms

Single-Use Vial

ALTEPLASE

Single-Use Vial

2 mg, 50 mg, 100 mg

ALTEPLASE

Common FDA Label Indication, Dosing, and Titration

Acute ischemic stroke, within 3 h of symptom onset

Acute pulmonary embolism

ST-segment elevation MI

Central venous catheter clearance

ALTEPLASE

MOA

fibrinolysis by binding to fibrin in a thrombus and converts entrapped plasminogen to plasmin

ALTEPLASE

Contraindications

Active internal bleeding

recent intracranial or intraspinal surgery or trauma within 2 month

prior intracranial hemorrhage, ischemic stroke within 3 mo

severe uncontrolled hypertension

anticoagulants with elevated laboratory tests

thrombocytopeniaacute bacterial endocarditis

ALTEPLASE

Adverse Reactions

Intracranial hemorrhage

Anaphylaxis, angioedema, cardiac arrhythmia, pulmonary edema, retroperitoneal hemorrhage

ALTEPLASE

Key Patient Counseling Points

Monitor for bleeding

allergic reactions with administration

EVOLOCUMAB

generic

Repatha

EVOLOCUMAB

Dosage Forms

Prefilled Syringe

Solution Autoinjector

Solution Cartridge

EVOLOCUMAB

Prefilled Syringe

Solution Autoinjector

140mg/1 mL

EVOLOCUMAB

Solution Cartridge

420mg/3.5 mL

EVOLOCUMAB

Common FDA Label Indication, Dosing, and Titration

Hyperlipidemia

Prevention of cardiovascular events

EVOLOCUMAB

MOA

PCSK9 Inhibitor

EVOLOCUMAB

Adverse Reactions

Nasopharyngitis

Angioedema

hypersensitivity reactions

CHLORPHENIRAMINE

generic

Chlor-Trimeton

CHLORPHENIRAMINE

Dosage Forms

Tablet

Tablet ER

Syrup

Liquid

CHLORPHENIRAMINE

Tablet

4 mg

CHLORPHENIRAMINE

Tablet, Extended Release

12 mg

CHLORPHENIRAMINE

Syrup

2mg/5 mL

CHLORPHENIRAMINE

Liquid

2 mg/1 mL

CHLORPHENIRAMINE

Common Self-Care Indications, Titration, and Dosing

Allergic rhinitis

CHLORPHENIRAMINE

MOA

blocks the H1-receptor

CHLORPHENIRAMINE

Contraindications

Narrow-angle glaucoma

bladder obstruction

BPH

use during acute asthmatic attacks

CHLORPHENIRAMINE

Adverse Reactions

Somnolence

Arrhythmias

seizure

CHLORPHENIRAMINE

Key Patient Counseling Points

Avoid allergic triggers

Use nasal wetting solutions

Avoid alcohol and activities requiring mental alertness

Take with full glass of water; may take with food if stomach upset occurs

Tablets are scored - pediatric dose

Avoid use in elderly pt

CHOLECALCIFEROL

generic

(VITAMIN D3)

D-Vi-Sol

CHOLECALCIFEROL

Dosage Forms

Tablet

Chewable Tablet

Capsule

Liquid

CHOLECALCIFEROL

Tablet

400 units, 800 units, 1000 units, 2000 units, 3000 units, 5000 units, 10,000 units, 50,000 units

CHOLECALCIFEROL

Chewable Tablet

400 units, 2000 units

CHOLECALCIFEROL

Capsule

1000 units, 2000 units, 5000 units, 10,000 units, 25,000 units, 50,000 units

CHOLECALCIFEROL

Liquid

400 units/mL, 5000 units/mL

CHOLECALCIFEROL

Common Self-Care Indications, Titration, and Dosing

Dietary Supplementation

CHOLECALCIFEROL

MOA

1,25-dihydroxyvitamin D (calcitriol), which binds to the intracellular vitamin D receptor

CHOLECALCIFEROL

Dose Adjustment Renal

yes

CHOLECALCIFEROL

Contraindications

Hypercalcemia

hypersensitivity malabsorption syndrome

evidence of vitamin D toxicity

CHOLECALCIFEROL

Adverse Reactions

None known

Hypercalcemia

CHOLECALCIFEROL

Key Patient Counseling Points

Few foods contain vitamin D, and dermal synthesis requires sun exposure

Do not exceed the RDA as excessive vitamin D

Some formulations contain sodium or glucose

caution for patients with diabetes or hypertension

EVOLOCUMAB

Key Patient Counseling Points

Store in refrigerator and do not freeze

room temperature for a maximum of 30 d

Protect from light

Do not shake

Allow syringe and autoinjector to warm to room temperature for 30 min and allow Pushtronex cartridge to warm for 45 min before use

Inject into abdomen, thigh, or upper arm. Rotate injection sites

Take a missed dose as soon as you remember, if within 7 d of missed dose

If using the every 2-wk dose, inject the next dose based on original schedule

If using the once-monthly dose, inject the dose and start a new schedule using this date.