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neuroscience
study of structure and the function of the nervous system
what is a nerve
made up of billions of neurons
peripheral nervous system
nerves that run from the spinal cord through the body. connect to muscles and glans. receives sensations (except smell).
central nervous system
spinal cord and brain
what does the spinal cord recieve
sensory signals
reflexes
if a signal is life or death it is a reflex. a reflex is an automatic action that requires no thought.
if the signal requires cognition or thinking, it travels to...
the brain
if a motor action is required through reflex or cognition, it is relayed back through the....
peripheral nervous system
if sensory neurons...they travel from the sensory organs to the
central nervous system
two divisions of the motor aspect of the PNS are...
somatic and autonomic
somatic ns
voluntary action - one we chose to do through cognition
somatic ns communicates through...
motor neurons
motor cortex
in the frontal lobe of the brain...communicates the voluntary action we want to take
autonomic ns
involuntary actions - muscles and gland movements you can't control
brain stem
regulates heartbeat and breathing - involuntary actions
two parts of autonomic ns
sympathetic and parasympathetic
sympathetic ns
prepares us for fight or flight
what does sympathetic ns do:
increases everything for survival
what does the sympathetic ns response not increase:
bladder contracts, digestion slows
parasympathetic ns
paramedics coming in to reverse everything aroused by sympathetic ns - back to homeostasis
neurotransmitters
how neurons communicate - chemical messengers
glial cells
provide nutrients and protection and waste transport - strengthen connections
how does nervous system work?
neurons receive sensory info (peripheral), carries it to CNS (brain, unless reflex), then neurons transmit info to muscles and the glands (motor cortex)
3 different types of neurons
sensory (afferent) PNS, interneurons CNS, motor (efferent) PNS
sensory neurons
PNS! found in skin cells and process somatosensation - balance, hearing, taste (the senses)
interneurons
CNS! percieve sensation coming and communicate with motor neurons for action. spinal cord to brain.
motor neurons
PNS! relay messages to muscles and glands
effectors
muscles and glands cells
myasthenia gravis
autoimmune disease the is due to weakness in voluntary muscles (somatic) due to error in how nerve signal is sent to the muscle (motor neurons). deterioration of ach neurons in the peripheral ns.
antibodies
alter or destroy neurotransmitter receptors at the muscle sites
nerve
bundle of neurons
dendrite
recieve incoming neurotransmitters
cell body
negative charge when at rest
excitatory neurotransmitters
if they attach to the dendrites, a rush of positive ions flood into the cell body
axon
conducting fiber that electricity fires through from the cell body
action potential
when the electric charge from the cell body reaches the axon - if it doesn't, electric charge dies
myelin sheath
bubbles of fatty tissue that protects the axon like insulation - made up of glial cells
what do neurons eat
glucose or sugar
multiple sclerosis
this degenerative disorder happens when myelin sheath breaks down
axon terminal/terminal buttons/branches
stores neurotransmitters
synapse
space between two neurons where the axon terminal releases neurotransmitters
what happens to neurotransmitters after they are released into synapse
some go back into the pre-synaptic neuron, some absorbed into post synaptic neuron
dendrites connect to the...
cell body of the next neuron
resting potential
if neuron is not firing it is at rest
at rest the cell body has a...
negative charge (-70mv)
outside the cell body has a
positive charge
inhibitory neurotransmitter
causes positive ions to be pumped out of the cell body
when the positive ions flood into the negative cell body (-70) it changes to the threshold which is...
-55mv
if the threshold isn't met.. nothing happens which is called
all or nothing response
reuptake
leftover neurotransmitters get reabsorbed by the pre synaptic axon terminal
what do problems with reuptake cause
schizophrenia
repolarization
after action potential. positive ions are pumped out of the cell body so the cell returns to resting state
refractory period
resting period after repolarization where the cell is resting and cant fire
hyperpolarization
during refractory period charge is less than -70mv , meaning it cannot fire.
acetylcholine neurotransmitter
enables muscle action, learning, and memory
alzheimers
caused by degeneration of ach neurons
dopamine
influences movement, learning, attention, and emotion. feel good neurotransmitter.
dopamine can cause addiction when...
dopamine reward pathway is activated
schizophrenia can occur when...(dopamine hypothesis)
there is too much dopamine due to problems with reuptake
parkinson's
deterioration or low levels of dopamine can cause parkinsons disease
serotonin
affects mood, hunger, sleep and arousal
too little serotonin
DEPRESSION AND ANXIETY (s)
norepinephrine
controls alertness and arousal.
too little norepinephrine
depression and anxiety
GABA
involved in sleep and relaxation.
gaba is what type of neurotransmitter
inhibitory - slows neural firing down
too little gaba causes:
anxiety disorders, insomnia, seizures -- epiliepsy
gulutamate
involved in learning and long term memory
glutamate is what type of neurotransmitter
excitatory - more neural firing
too much glutamate causes
seizures, migranes, and heart problems
MSG
preservative in many foods that contains glutamate
endorphins
serve as painkillers. produces when we exercise, eat spicy foods, are excited, or in love
opiates (dtaae)
drugs that act as endorphins
substance p
CNS. works with glutamate in transmission of pain.
substance p is an
excitatory neurotransmitter
where is substance p released
pns - at sensory nerves, causes inflammation
opioids block what?
block the release of substance p
agonist drugs
increase the amount of neurotransmitters at the synapse
agonist drugs do what
mimic neurotransmitters or they bind to the receptor sites and block reuptake, so more of the neurotransmitters build up.
most antidepressants are
agonist drugs- block reuptake
antagonist drugs
decrease the amount of neurotransmitters available in the synapse
antagonist drugs do what?
block release of neurotransmitters at terminal branches, or block receptor sites on the dendrite, decreasing amount of neurotransmitters being created
psychoactive drugs
chemical substances that alter perceptions - cause withdraw, tolerance, dependence
depressants
slow down central NS
what do depressants act as
GABA
depressants are
agonists
what do depressants to the body
supress rem sleep, decrease memory function
opiates
ACT as endorphins
examples of opiates
opium, heroin, and morphine
opiates are
stimulants! speed up the central nervous system
hallucinogens
cause an extrasensory experience!
marijuana (hallucinogens) are
agonists - block reuptake
what does the brain stem control
basic life functions - heart rate, breathing, conciousness
medulla oblongata
regulates heartbeat, breathing, and vomiting
if medulla is damaged
in can cause death
recticular activating system
nerve that connects spinal cord to the thalamus.
what does the recticular activating system do:
FILTERS!!! sleep wake cycle, voluntary movements, paralyzes the body in rem sleep, rapid eye movement
if the recticular activating system is injured
it may result in a coma
habituation
an organism's decreasing response to a stimulus with repeated exposure to it
thalamus (limbic system)
recieves info from all senses (except smell) - sends to proper cortex