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Central Dogma of Biology
The process of making a protein of DNA
Cell Theory
1.) Every cell is made of pre-existing cells
2.) The cell is the basic unit of structure and function of all living things
3.) Every living thing is made of at least 1 cell
Multicellular
Organisms made of multiple cells working together
Prokaryote
Cells without a nucleus (bacteria)
Eukaryote
Cells with a nucleus and membrane-bound organelles
Nucleoid
The area where DNA is found in prokaryotes
DNA
Genetic material that contains instructions for everything the cell needs
Double Helix
The twisted ladder shape of DNA
Gene
A segment of DNA that codes for one specific trait or protein
Nucleotide
The building blocks of DNA and RNA
Nucleus
Stores and protects DNA
Nuclear Membrane
Double phospholipid bilayer surrounding the nucleus
Nuclear Pores
Holes in the nuclear membrane that regulate what enters/exits
Nucleolus
Dark area inside nucleus where rRNA is made
Transcription
Process of making mRNA from DNA
Translation
Process of reading mRNA to make a polypeptide
mRNA
Messenger RNA; the “cheap copy” of DNA that carries instructions
Ribosome
The organelle that reads mRNA and makes polypeptide chains
Large Subunit
The top part of the ribosome
Small Subunit
The bottom part of the ribosome
rRNA
Ribosomal RNA; what ribosome are made of
Polypeptide Chain
Chain of amino acids; primary structure of protein
Amino Acids
Building blocks (monomers) of proteins
Peptide Bonds
Bonds that connect amino acids together
Rough Endoplasmic Reticulum
ER with ribosomes; folds polypeptide chains into proteins
Smooth Endoplasmic Reticulum
ER without ribosomes; makes lipids and detoxifies
Endoplasmic Reticulum
Folded membranes attached to the nucleus
Golgi Apparatus
Organelle that modifies and packages proteins
Transport Vesicle
Membrane sac that moves materials between organelles
Secretory Vesicle
Membrane sac that moves materials out of the cell
Vesicle
Membrane around any substance that needs temporary protection
Phospholipid
Type of lipid that makes up cell membranes
Phospholipid Bilayer
Double layer of phospholipids in membranes
Polar
Hydrolitic part of phospholipid (Head)
Non-Polar
Hydrophobic part of phospholipid (Tails)
Exocytosis
Process where materials leave the cell
Cell Membrane
Outer boundary of the cell
Endomembrane System
Organelles that work together to make and transport proteins
Membrane-Bound Organelles
Organelles surrounded by membranes
Organelle
Specialized structures inside cells that perform specific functions
Cytoplasm
Jelly-like substance inside cells where organelles float
Protein
Folded polypeptide chain that performs specific functions
Primary Structure
The sequence of amino acids in a polypeptide chain
Folding
Process that turns polypeptide chains into functional proteins
Secretion
Process of releasing materials from a cell
Modification
Changes made to proteins in the Golgi Apparatus
Membrane Recycling
How cells reuse phospholipids without wasting them
Three Domains
Bactera, Archaea, Eurkaryotes
Kingdoms
Subdivisions of Eukaryotes (Protista, Plantae, Animalia, Fungi)
Transcription vs Translation
DNA to mRNA vs mRNA to Protein