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Oxytocin
Hypothalamus (stored/released by Posterior Pituitary)
Uterine contraction, trigger for milk ejection, neurotransmitter in brain
target: uterus, breasts
Regulated by: Nervous System
ADH (Antidiuretic Hormone)
Hypothalamus (stored/released by Posterior Pituitary)
Inhibits urine formation, regulates water balance (kidney reabsorption)
target: kidneys
Regulated by: Nervous System
TSH (Thyrotropin)
Anterior Pituitary
Stimulates thyroid activity
target: thyroid
Regulated by: TRH Hormone
ACTH (Adrenocorticotropic)
Anterior Pituitary
Corticosteroid release
target: Adrenal Cortex
Regulated by: CRH hormone
GH (Growth Hormone)
Anterior Pituitary
Metabolism
Glycogen breakdown and glucose release to blood (anti-insulin effect)
Mediates growth
insulin-like growth factors (IGFs)
IGFs stimulate
Nutrient uptake
formation and deposition collagen/bone
Target: Bone and skeletal muscle
Regulated by: GHRH hormone (stimulates) and Somatostatin (inhibits)
PRL (Prolactin)
Anterior Pituitary
Stimulates milk production
target: breasts
Regulated by: Dopamine hormone
FSH (Follicle-Stimulating)
Anterior Pituitary
Gamete production (how sperm and eggs are made)
target: gonads
Regulated by: GnRH hormone
LH (Luteinizing)
Anterior Pituitary
Gonadal hormone production (Estrogen, testosterone)
target: gonads
Regulated by: GnRH hormone
T3/T4 (Triiodothyronine/Thyroxine)
Follicular cells of Thyroid
Major metabolic hormone
-increased metabolic rate & heat production
Regulated by: TSH hormone
PTH (Parathyroid)
Parathyroid
Increases calcium levels in blood
target: osteoclasts, kidneys, small intestine
Regulated by: Humoral Stimulus
Calcitonin
Parafollicular cells of Thyroid gland
Decreases calcium levels in blood
target: osteoclasts, kidneys
Regulated by: Humoral Stimulus
Aldosterone
Zona Glomerulosa of Adrenal Cortex
Stimulates sodium reabsorption (water retention) by kidneys.
Eliminates high levels of potassium
target: kidneys
Regulated by: Angiotensin 2 hormone
Cortisol
Zona Fasciculata of Adrenal Cortex
Stress response, blood glucose homeostasis, fluid retention, suppression of inflammation response
Regulated by: ACTH hormone
Androgens
Zona Reticularis of Adrenal Cortex
Female libido, pubic hair.
Regulated by: ACTH hormone
Epinephrine/Norepinephrine
Adrenal Medulla
Increased HR, increased metabolic rate, increase blood pressure.
Regulated by: Nervous System
Insulin
Pancreas
Released by beta cells. Decrease blood glucose.
target: liver
Regulated by: Humoral Stimulus
Glucagon
Pancreas
Released by alpha cells. Increase blood glucose.
Liver
Regulated by: Humoral Stimulus
Estrogen/Progesterone
Ovaries
Maturation of reproductive organs during puberty (breast development, menstrual cycle)
Regulated by: LH/FSH hormone
Regulated by: Humoral Stimulus
Testosterone
Testes
Produce sperm and male sex hormones
Regulated by: LH/FSH hormone
Resistin
Adipose tissue
Suppresses appetite, increases energy expenditure.
target: brain
Regulated by: Humoral Stimulus
EPO (Erythropoietin)
Kidney
Secreted in response to hypoxia. Stimulates production of red blood cells
target: red bone marrow
Regulated by: Humoral Stimulus
Natriuretic Peptides
Heart
Kidney: inhibits sodium reabsorption and renin release
Adrenal cortex: inhibits secretion of aldosterone, decreases blood pressure
target: kidney and adrenal cortex
Regulated by: Humoral Stimulus