Rheumatoid Arthritis vs. Osteoarthritis: Extra-Articular Manifestations

Flashcards covering the extra-articular manifestations of Rheumatoid Arthritis compared to Osteoarthritis, including heart, lung, blood, and gland involvement.

How do Rheumatoid Arthritis (RA) and Osteoarthritis (OA) differ in terms of systemic or extra-articular involvement?

RA is a whole-body disease, whereas OA has nothing outside the joint at all.

What are the six places outside the joint affected by RA that OA never touches?

Lung, heart sac, eye, nodule, neck, and spleen.

What lung involvement is associated with Rheumatoid Arthritis?

Interstitial lung disease, nodules in the lung (fibrosis), Caplan syndrome, and pleuritis.

What is Caplan syndrome?

RA nodules PLUS a dusty-lung disease.

What heart and lung lining conditions occur in Rheumatoid Arthritis?

Pleuritis and pericarditis, which affect the linings of the lung and heart.

What is Felty syndrome?

A condition characterized by a big spleen (splenomegaly) with low blood counts.

What does the mnemonic SANTA stand for regarding Felty syndrome?

Splenomegaly, Anemia, Neutropenia, Thrombocytopenia, Arthritis.

What symptoms are associated with Sjogren syndrome in RA?

Sjogren syndrome gives dry eyes and a dry mouth.