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what is the longest phase of the cell cycle
interphase
what is the first step of the cell cycle
G1
what happens to the cell during G1 phase
the cell increases in volume
what is the second phase of the cell cycle
s phase
what happens to the cell during s phase
DNA replication and copying of chromosomes
what is a holder
where a cell stays before moving to the next phase of the cycle until it has what it needs for cell division
what is an example of a holder
G0
what are two example of cells that never get past g1/g0
brain and cardiac muscle cells
what is the third phase of the cell cycle
g2
what happens in g2 phase
final step of preparation, organalles and DNA are checked
what is the last phase of the cell cycle
mitosis
what is the shortest phase of the cell cycle
mitotic phase
what happens during mitosis phase
cell undergoes division and two identical daughter cells are formed
what is the acronym for mitosis steps
PMAT
during prophase what happens to the nuclear membrane
it starts to break down
during prophase what happens to the centrioles
they begin to move to opposite sides
during prophase what happens to the spindle fibers
they start to appear
during prophase what happens to the chromosomes
they become denser and more visible
during prophase what do the chrosomes look like
the letter x held together by a dot in the middle
what are two chromosomes together called during mitosis
sister chromatids
during prophase what holds the sister chromatids together
centromeres
what make sister chromatids visible under microscropes
their centromeres
during metaphase where are the chromosomes
lined up in the middle of the cell
during metaphase what happens to the spindle fibers
one side attaches to the centromere of the chromatids and the other to the edge of the cell
during anaphase what happens to the chromosomes
the spindle fibers pull the chromosomes apart and bring each to opposite sides of the cell
during telophase of an animal cell what happens
the cytoplasm is pinched by cleavage furrow until the cell splits into two
during telophase of a plant cell what happens
a cell plate forms and splits the cell into two
what does cytokinesis mean
dividing the cytoplasm
after PMAT what happens to the two identical daughter cells
the chromosomes unravel DNA and protein and turn back into chromatin
what is the longest phase in interphase
G1
what is the primary checkpoint in interphase
G1
what is telomerase
an enzyme that replicated DNA
when is telomerase active
in utero and in cancer
what is cancer
uncontrolled cell growth
what does benign mean
non cancerous
what does malignant mean
cancerous and metastasis
what does metastasis mean
has the ability to spread
what is apoptosis
programmed cell death
T/F cancer does not go through apoptosis
True
what is contact inhibition
the ability for cells to divide when they come in contact with each other
T/F tumor cells are constantly repairing and producing telomerase
true
what are proto-oncogenes
controls cell division
what are tumor suppressor genes
regulate cell division and reproduction
T/F asexual reproduction does not lead to offspring identical to parent organism
False
what is different about asexual reproduction
only one cell is needed
what is binary fission
when a single bacteria cell splits itself into two identical daughter cells
how long does it take approx. for each bacteria cell to divide
20 minutes
what is a karytoype
a chart showing the chromosomes of an individual from largest to smallest
what does an odd number of chromosomes mean
down syndrome
T/F the acrosome of sperm contains digestive enzymes
True
how many times does pmat occur in meiosis
twice
what does meiosis produce
gametes/sex cells
what is synapsis
the fusion of chromosome pairs at the start of meiosis
during prophase 1 what happens to the nuclear membrane
it starts to break down
during prophase 1 what happens to the spindle fibers
they start to form
during prophase 1 what happens to the chromosomes
the homologous chromosomes start to pair up
how many pairs of chromosomes as a result of meiosis
23
what is a tetrad
two pairs of chromosomes together
when does crossing over occur in meiosis
prophase 1
what is crossing over
when homologous chromosomes exchange genetic information
during metaphase 1
after the first PMAT in meiosis is it haploid or diploid
haploid
during prophase II what happens to the spindle fibers
they are all over the cell
during metaphase II what happens to the chromosomes
they are in the middle attached to the spindle fibers
during anaphase II what happens to the chromosomes
the pairs are pulled apart to either side of the cell by the spindle fibers
what happens during telophase II
the cleavage furrow starts to pinch
what is left after PMAT II of meiosis
four genetic diverse haploid diploid daughter cells
what is oogenesis
the process in a female body that produces eggs
what are the end products of oogenesis
one big egg cell and three nonviable little polar bodies
what is independent assortment
the possibilities of how chromosomes align them self, combination possibilities of genes
how many possible combinations are there for any given egg or sperm, not including crossing over
64 trillion
T/F eggs contain lots of cytoplasm
True
what is nondisjunction
the failure of chromosomes to pull apart through meiosis I and II
what is the result of nondisjunction
down syndrome, uneven chromsomes
what is turner female syndrome
women only have one x sex chromosome and are non fertile
what is a characteristic of turner female syndrome
underdeveloped external and internal sexual characteristics
what is klinefelter syndrome
males born with one y and two x sex chromosomes
what is a characteristic of klinefelter syndrome
enhanced sexual characteristic development, more like female development
what is the most severe form of down syndrome
trisomic 21
what is trisomic 21
an extra chromosome on karyotype 21
what is gene translocation
part of a chromosome (one gene) relocates to different chromosome
what is gene deletion
when an entire gene is deleted
what is gene duplication
exact copy of the same gene is duplicated
what is p53
a protein that checks the DNA for any mutations and either repairs or induces cell death, apoptosis
where does p53 take place
G1
what are histones
proteins that allow the DNA to be wrapped tightly to form chromosomes
what are chromatin
loose DNA in the nuclear envelope, during interphase, unable to see chromosomes at this point
what is encapsulated cancer
noninvasive, does not spread
what is cytokinesis
splitting of the cytoplasm at the end of telophase
during interphase what is inside of the nuclear envelope
chromatin
what is a genome
the entire DNA 6-8 ft long wrapped around histone proteins
what does the DNA look like in prokaryotic cells
circular
what is the order of asexual reproduction
replication of DNA and then cell division
are proto-oncogenes a positive or negative cell cycle regulator
positive
what is the purpose of mitosis cell division
procreation of somatic cells
what is the purpose of meiosis cell division
recreate reproductive cells
how many and what type of cells are produced from meiosis
23 haploid, 1 cell to 2 identical cells
how many and what type of cells are produced from mitosis
46 diploid, 1 cell to 4 different cells