General Lab Practice Solo 1 Review & Kahoot & Crossword

__________ is the closeness of the test value to the true mean

Accuracy

_________ is reproducibility among replicate determinations of a sample

Precision

_________ is the closeness of agreement between results of successive measurements carried out under the same conditions

Repeatability

________ is the closeness of agreement between results of measurements performed under changed conditions of measurements

Reproducibility

__________: the same percentage of the concentration being measured so the absolute magnitude increases as the concentration increases

Proportional random error

__________ is caused by intrinsic properties of the method; due to chance

Random error

Error that is always in one direction and has the same magnitude regardless of the concentration is ____________

Constant systematic error

What type of error has occurred when repeated observations of a measure of an analyte demonstrate wide variation in values

Random error

The type of error that occurs with a constant or predictable difference or trend, either positive or negative, and thus will directly affect the estimate of the mean is _________

Systematic error

The ability of an analytical method to determine solely the component(s) it purports to measure

Analytical specificity

The ability of an analytical method to detect small quantities of the component(s) being measured

Analytical Sensitivity

The reliability of a test to be negative in the absence of the disease it was designed to detect

Clinical specificity

The reliability of a test to be positive in the presence of the disease it was designed to detect

Clinical sensitivity

__________ is the measure of dispersion around the mean in a Gaussian distribution

Standard deviation

The statistical analysis used to compare values obtained by a new method with those obtained by an established method without the use of a statistical table is ____________

Linear regression

The following were obtained from a set of automated white blood cell counts performed on 50 samples.

Standard deviations: 163.2 microliter

Mean: 14550

Calculate CV

CV = 1.2%

What is the predictive value of a test in which 450 tested individuals with positive test results have the disease and 45 tested individuals with positive test results did not have the disease?

90.9%

Calculate the clinical sensitivity for the following data: In a group of 90 patients diagnosed with sickle cell disease, 10 tested negatively for it. The clinical sensitivity of this test is

88.8%

The mean for hemoglobin is 15.0 g/dL and the standard deviation is 0.30. The acceptable control range is ±2 standard deviations. The allowable limits for the control in g/dL are

14.40-15.60

A clinical chemistry lab insists on 95% control limits for serum cholesterol. From previous data, it has been shown that the mean of the daily control serum is 300 mg/dL with a variance of 100mg/dL. If today you obtained a value of 345 mg/dL for the control serum you would conclude

The result is outside limits of acceptance

If your new chemistry analyzer has a variance of 100 what would the standard deviation be?

10

±2SD is a ___ % confidence interval

95

If your chemistry analyzer has a mean of 200 and a variance of 100 what is the 95% confidence interval

180-220

You are performing a precision study each value is always 2 points greater than the previous. This is an example of

Constant systematic error

Comparison of values from a new method and an established method without a statistical table

Linear regression

________ is reproducibility among replicate determinations of sample

Precision

What is the predictive value? 220 positive test with the disease, 45 positive test without the disease

83%

If the correlation coefficient is zero

There is no correlation.

Calculate clinical sensitivity: 80 patients with sickle cell, 8 tested negative for it

90

By assaying a sample with a known value, you are checking the

accuracy

The closeness of the test value to the true mean

Accuracy

Error in which the magnitude of error increases as the concentration increases

Proportional systematic

A measure of the dispersion of random errors

Imprecision

Ability to detect small quantities of the measured analyte

Analytical sensitivity

Closeness of agreement of a single measurement with the true value

Accuracy

Closeness of agreement between independent results of measurements obtained under stipulated conditions

Precision

The effect of a component on the accuracy of the measurement of another component

Interference

Closeness of agreement between results of measurements performed under changed conditions

Reproducibilty

Smallest result distinguishable from a suitable blank

Detection Limit

Ability of an analytical method to determine solely the analyte is supposed to measure

Analytical specificity

Closeness of agreement between results of successive measurements carried out under the same conditions

Recovery

The difference between the average value and the true value

Bias

The closeness of agreement of the mean value with the true value

Trueness