Central Dogma Molecular Biology

Central Dogma of Molecular Biology

Describes the flow of genetic information: DNA → RNA → Protein.

Who coined the term 'Central Dogma'?

Francis Crick (~1965) coined the term.

Function of DNA

Stores genetic information and provides instructions for protein synthesis.

What is the role of RNA?

Acts as a messenger that carries genetic instructions from DNA to ribosomes.

Location of DNA

Located in chromosomes within the nucleus.

Transcription

The process where DNA is converted to mRNA (messenger RNA) in the nucleus.

Translation

The process where mRNA is translated into protein (amino acid sequence) at the ribosome in the cytoplasm.

Exceptions to the Central Dogma

Retroviruses, such as HIV, do not follow this pathway and use reverse transcription (RNA → DNA).

What are the two main processes of the Central Dogma?

Transcription (DNA → RNA) and Translation (RNA → Protein).

Key takeaway of the Central Dogma

DNA codes for proteins, which determine cell structure and function.