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Central nervous system (CNS)
Brain
Spinal cord
Peripheral nervous system
31 pairs of spinal nerves
12 pairs cranial nerves
Peripheral autonomic and sensory ganglia
CNS Major divisions
Cerebral hemispheres, diencephalon, brainstem, cerebellum
Diencephalon
Thalamus, hypothalamus, subthalamus
Brainstem
Midbrain, pons, medulla
Cerebral cortex
Planning & execution of actions including speech and language
Interpretation and moderation of sensation
Subcortex
Supports the functions of the cortex and regulate cortical activity
Includes basal ganglia and diencephalon
Limbic system
Regulation of emotion
Memory formation
Center of our ability to learn, understand!
Cerebral hemispheres purpose
Frontal lobe
Executive functioning and motor production
Most anterior part of the brain
Critical for language production
Center for consciousness
Broca’s area
Parietal lobe
Sensory integration & information
Temporal lobe
Auditory processing and comprehension
Primary & secondary auditory cortex
Wernicke’s Area
Some hearing & visual perceptions
Occipital lobe
Visual processing
Limbic Lobe
(Insula)
A critical area for both sensory and motor functions
Related to speech and language skills - but not fully understood
Sulci
Grooves or valleys in the brain
Fissures are very deep versions of this
Gyri
Ridges or bumps in the brain
Key cortical areas for communication• Broca’s area (44 & 45)
• Broca’s area (44 & 45)
• inferior frontal gyrus
• Wernicke’s area (22)
• Superior temporal gyrus
• Primary auditory cortex (41 & 42)
• Primary sensory cortex (2)
• Primary (4) & pre (6) motor cortex
• Primary visual cortex (17)
• Supramarginal gyrus (40)
• Angular gyrus (39)
1
Precentral gyrus
Primary motor cortex
Controls bodily movements
2
Central sulcus
Divides frontal and parietal lobes
3
Postcentral gyrus
Primary sensory cortex
Processes bodily sensations
4
Supramarginal gyrus
Broad range of language formulation
^ Including semantic and phonologic processing
5
Angular gyrus
Semantic processing
Repetition
Metaphor comprehension
6
Pre-occipital notch
Separates occipital and temporal lobes
7
Lateral sulcus
Separates frontal & parietal lobes from the temporal lobe
8
Heschl’s / transverse gyrus
Responsible for the reception of auditory stimuli including:
Frequency
Location
Intensity
Found in primary auditory cortex
9
Superior temporal gyrus
Associated more closely with language input than output
10
Inferior frontal gyrus
Critical for higher cognitive functions like judgement, planning, decision making, executive functioning, reasoning
11
Middle frontal gyrus
Critical for higher cognitive functions like judgement, planning, decision making, executive functioning, reasoning
12
Superior frontal gyrus
Critical for higher cognitive functions like judgement, planning, decision making, executive functioning, reasoning
13
Medial / longitudinal fissure
Separates the two hemispheres
A
Broca’s area
Associated with speech production and articulation
Broadmann numbers 44&45
B
Wernicke’s area
Associated with speech comprehension
Broadmann number 22
Basal ganglia
a group of nuclei in the brain that are involved in a variety of functions, including motor control, cognition, and emotions
A large network of embedded gray matter structures (= a cluster of nuclei)
• Caudate nucleus
• Globus pallidus
• Putamen
*Substantia Nigra
*Subthalamic nucleus
•Motor coordination
•Pathologic conditions
Thalamus
Largest diencephalon structure
Sensory & motor relay center
Consciousness & alertness
Center of the forebrain & posterior
to the basal ganglia
The relay station
Subcortical structures
Responsible for important emotions such as: pleasure, mating, feeding, emotions, memory, learning, motivation, fight or flight
Basal ganglia network connections
Thalamus → cerebral cortex → Striatum → GPi
Basal ganglia functions
Releasing desired movements and cognitive process
Inhibiting competing or undesired movements and thoughts
Hypothalamus
Cone-shaped structure beneath the thalamus
Bounded by the optic chiasm
Nonconscious regulation of bodily homeostasis and hormone secretion via the pituitary gland
Limbic systems structures
Hippocampus
Amygdala
Cingulate gyrus
Neurons
Basic structural and functional unit of the nervous system
A
Dendrite
Receive signals from other cells
B
Cell body
Organizes & keeps the cells functional
C
Nucleus
Controls the entire neuron
D
Axon
Transfers signals to other cells & organs
E
Node of Ranvier
Allow diffusion of ions
F
Axon Terminal
Forms junctions with other cells
G
Schwann Cell
Produces the myelin sheath / glial cells
H
Myelin Sheath
Increases the speed of the signal
Motor neurons
(efferent)
Causes muscles to contract or glands to secret
Interneurons
Most neurons in CNS
Process information carried by both motor and sensory neurons
Sensory neurons
(afferent)
Carry sensory information from PNS to CNS
Glial cells
Non neural cells providing support, nutrition, and maintenance for neurons
Astrocytes
Microglia
Oligodendrocytes
Schwann cells
Gray matter
In CNS neural tissues
Grayish/brownish cell bodies
Process information
White matter
In CNS neural tissues
White myelin sheath (fatty covering) around axon
Transmit information
Nerves
Cranial and spinal nerves in PNS
Ganglion
(ganglia)
Groups of neuronal cell bodies and dendrites
Pathways/tracts
Bundles of axons in the CNS
Nerves
Bundles of axons in the PNS