POPP Exam 2

herpes genitalis, zoster, varicella

Indications for acyclovir

reverse transcriptase

Enzyme needed for HIV viral replication

nucleoside RTI

ARV class of lamivudine

nucleoside RTI

ARV class of abacavir

nucleoside RTI

ARV class of emtricitabine

NNRTI

ARV class of rilpivirine

nucleotide RTI

ARV class of tenofovir

Epivir

Name brand lamivudine

Ziagen

Name brand abacavir

Emtriva

Name brand emtricitabine

Edurant

Name brand rilpivirine

Viread

Name brand tenofovir

tenofovir

Generic of Viread

rilpivirine

Generic of Edurant

abacavir

Generic of Ziagen

lamivudine

Generic of Epivir

emtricitabine, tenofovir

Generics in Truvada

emtricitabine, tenofovir

Generics in Descovy

Truvada, Descovy

Name brands of emtricitabine, tenofovir combo

protease inhibitor

ARV class of ritonavir

protease inhibitor

ARV class of atazanavir

integrase inhibitor

ARV class of dolutegravir

integrase inhibitor

ARV class of elvitegravir

integrase inhibitor

ARV class of bictegravir

integrase inhibitor

ARV class of cabotegravir

Norvir

Name brand ritonavir

ritonavir

Generic of Norvir

Reyataz

Name brand atazanavir

atazanavir

Generic of Reyataz

Tivicay

Name brand dolutegravir

dolutegravir

Generic of Tivicay

abacavir, dolutegravir, lamivudine

Generics in Triumeq

Triumeq

Name brand of abacavir, dolutegravir, lamivudine combo

elvitegravir, cobicistat, emtricitabine, tenofovir

Generics in Stribild and Genvoya

Stribild, Genvoya

Name brands of elvitegravir, cobicistat, emtricitabine, tenofovir combo

cobicistat

PK enhancer used in Stribild and Genvoya

pharmacokinetic enhancer

Category of cobicistat

bictegravir, emtricitabine, tenofovir

Generics in Biktarvy

Biktarvy

Name brand bictegravir, emtricitabine, tenofovir combo

cabotegravir, rilpivirine

Generics in Cabenuva

Cabenuva

Name brand cabotegravir, rilpivirine combo

injection 1/mo

Dosing of Cabenuva

Truvada, Descovy, Apretude

Name brands used for PrEP

ER injection

Formulation of Apretude

Q 2mo

Dosing of Apretude for PrEP

1wk

How long for full protection using cabotegravir in PrEP

3wk

How long for full protection with Truvada

Valtrex

Name brand valacyclovir

valacyclovir

Generic of Valtrex

500, 1000mg

Tablet strengths of valacyclovir

1g BID for 10 days

Initial episode for genital herpes dosing of valacyclovir

500mg BID for 3 days

Recurrent episode genital herpes dosing of valacyclovir

1g QD

Prophylaxis dosing for genital herpes of valacyclovir

1g TID for 7 days

Valacyclovir dosing for shingles

cold sores

Common name for herpes labialis

labialis

Herpes type that is known as cold sores

2g BID for 1 day

Valacyclovir dosing for herpes labialis

1g TID for 7 days

Valacyclovir dosing for varicella

Tamiflu

Name brand oseltamivir

oseltamivir

Generic of Tamiflu

neuraminidase inhibitor

Antiviral class of oseltamivir

capsule, powder for oral suspension

Dosage forms of oseltamivir

BID for 5 days

Oseltamivir dosing for flu tx

QD for 10 days

Oseltamivir dosing for flu prophylaxis

Xofluza

Name brand baloxavir

baloxavir

Generic of Xofluza

endonuclease inhibitor

Antiviral class of baloxavir

trivalent cations

What to avoid when taking baloxavir

single dose

How many doses for tx/prophylaxis of flu with baloxavir

within 2 days of symptoms

When should Tamiflu and Xofluza be initiated to be most effective?

Tivicay, Truvada + raltegravir

What drugs are used for PEP?

BID together

Dosing of Truvada+raltegravir for PEP

1QD

Dosing of Tivicay for PEP

4wk

Duration of PEP

no later than 72hrs post exposure

When should PEP be started?

tonic-clonic, absence, myoclonic

Types of generalized seizures

simple, complex

Types of partial seizures

focal

Other name for partial seizures

petit mal

Other name for absence seizures

generalized

What type of seizure affects both hemispheres of the brain?

absence

Type of seizure described by brief loss of consciousness, no convulsions, “blank stare”

tonic-clonic

Type of seizure described by loss of consciousness, stiffening, and jerking

complex partial

Type of seizure described by impaired awareness, repetitive movements, dazed state, confusion

simple partial

Type of seizure described by having awareness, possible limb movement, visual/sensory changes

barbiturate

Anticonvulsant class of phenobarbital

barbiturate

Anticonvulsant class of butalbital

succinimide

Anticonvulsant class of ethosuximide

sulfonamide

Anticonvulsant class of zonisamide

hydantoin

Anticonvulsant class of phenytoin

sedative

Indication of phenobarbital

partial, tonic-clonic

Types of seizures treated with phenobarbital

C4

Schedule of controlled substance of phenobarbital

tension headache

Only indication for butalbital

barbiturate, analgesic

Therapeutic categories of butalbital

absence seizures

Indication for ethosuximide

partial seizures

Indication for zonisamide

partial, tonic-clonic seizures

Indication for phenytoin

Zarontin

Name brand ethosuximide

ethosuximide

Generic of Zarontin

Zonegran

Name brand zonisamide