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Amino acids (4)
Glutamate
Aspartate
Glycine
GABA (y-aminobutyric acid)
What is GABA derived from?
Glutamate
What are monoamines derived from?
Amino acids
What are catecholamines synthesized from?
Tyrosine
What are examples of catecholamines?
Dopamine
Epinephrine (adrenaline)
Norepinephrine (noradrenaline)
What is an example of an in dopamine?
Serotonin
What is serotonin synthesized from?
Trytpothine
What is an acetylcholine?
A choline molecule that has been acetylated
What are acetylcholines important for?
Muscle contraction at the neuromuscular junction
What are examples of small molecules?
Nitric oxide
Carbon monoxide
What are two traits of small molecules?
Small
Nonpolar
What type of transmission are small molecules involved in?
Retrograde transmission
What type of transmitters are endocannabinoids?
Retrograde
What type of chains are neuropeptides?
Large polypeptide chains
The function of a neuropeptide depends on its ________.
Amino acids sequence
What are the types of neuropeptides?
Pituitary peptides
Hypothalamic peptides
Brain-gut peptides
Opioid peptides
Miscellaneous
Excitation of a neuron results in ____.
Depolarization of the post synaptic neuron
What is an example of an excitatory neurotransmitter?
Glutamate
What does an inhibitory neurotransmitter result in?
Hyperpolarization of the neuron
What are examples of inhibitory neurotransmitters?
Glycine
GABA
In skeletal muscles, acetylcholine is ______, while in cardiac muscle, it is ______.
Excitatory, inhibitory
In direct action, a neurotransmitter binds to an _____________.
Ionitropic receptor
What are examples of direct-action neurotransmitters?
Acetylcholine and amino acid neurotransmitters
In indirect action, action is promoted through ___________ like G proteins.
Second messenger molecules
Indirect action is mediated by _________. This is similar to how hormones work.
Metabotropic receptors.
What are examples of indirect-action molecules?
Monoamines, neuropeptides, small gas molecules
When neurotransmitters act as chemical messengers, they are called _______.
Neuromodulators