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What is buprenorphine
A partial opioid agonist used for pain and opioid use disorder.
What are the BIG side effects of buprenorphine
Respiratory depression, sedation, nausea, constipation.
What should the nurse monitor with buprenorphine
Respiratory rate, sedation, pain, and bowel movements.
What should patients avoid with buprenorphine
Alcohol and other sedating/CNS-depressant medications.
What reversal drug should be available with buprenorphine
Naloxone.
What type of drug is fentanyl
A strong opioid analgesic.
What is the biggest danger of fentanyl
Respiratory depression/apnea.
What should the nurse continuously monitor with fentanyl
Pulse oximetry, respiratory rate, and sedation.
What must NEVER be applied to a fentanyl patch
heat
Why can't you put heat on a fentanyl patch
Heat can increase fentanyl absorption → overdose.
Who can use a fentanyl patch
Opioid-tolerant patients.
What antidote should be available for fentanyl overdose
Naloxone.
What is flumazenil
A benzodiazepine antidote.
What does flumazenil reverse
Benzodiazepine sedation/overdose.
What is the BIG danger of flumazenil
seizures
Why can a patient become sedated again after flumazenil
Flumazenil has a shorter half-life, so the benzodiazepine can outlast it.
What should the nurse monitor after flumazenil
Respirations, LOC, and seizures.
What emergency equipment should be available with flumazenil
Airway and resuscitation equipment.
What is gabapentin mainly used for
Nerve pain and partial seizures.
What are common side effects of GABAPENTIN
Dizziness, sleepiness, ataxia, and edema.
What major safety issue occurs with gabapentin + opioids
Increased risk of respiratory depression.
Should gabapentin be stopped suddenly
no
Why shouldn't gabapentin be stopped suddenly
It can cause rebound effects/seizures.
What organ function is especially important to monitor with gabapentin
Kidney/renal function.
What is hydrocodone
An opioid pain medication.
What is the biggest danger for MORPHINE
Respiratory depression.
What other common side effects occur for MORPHINE
Sedation, constipation, nausea, dizziness.
What should the nurse assess before and after hydrocodone
Pain, sedation, and respiratory rate.
What should you watch if hydrocodone is combined with acetaminophen
The patient's total daily acetaminophen dose.
What should patients avoid with hydrocodone
Alcohol and driving when sedated.
What type of drug is ibuprofen
An NSAID.
What is ibuprofen used for
Pain, inflammation, and fever.
What are the TWO big problems with ibuprofen
GI bleeding + kidney injury.
What stool finding could indicate GI bleeding
Black/tarry stool.
What vomit finding could indicate GI bleeding
Coffee-ground emesis.
What should the patient take ibuprofen with
Food or milk.
What should patients avoid taking with ibuprofen
Other NSAIDs.
What should the nurse monitor for IBUPROFEN
GI bleeding, renal function, and BP.
What type of drug is lorazepam
A benzodiazepine.
What is lorazepam used for
Anxiety, alcohol withdrawal, seizures, and sedation.
What are the major side effects for LORAZEPAM (Ativan)
Sedation, respiratory depression, dizziness, ataxia, confusion.
What happens if long-term lorazepam is stopped suddenly
Withdrawal and potentially life-threatening seizures.
What should patients NOT mix with lorazepam
Alcohol or other CNS depressants.
What should the nurse watch for in older adults
Falls, confusion, and oversedation.
What antidote may be used for benzodiazepine overdose
Flumazenil.
What type of drug is morphine
An opioid analgesic.
What is the BIGGEST danger for HYDROCODONE
Respiratory depression.
What other side effects should you remember of MORPHINE
Sedation, constipation, nausea/vomiting, itching, hypotension.
What should the nurse check before giving morphine
RR, sedation, pain, and BP.
What antidote should be available for Buprenorphine (Buprenex/Subutex)
Naloxone.
Why can morphine cause itching and low BP
It can cause histamine release.
Why is morphine considered high-alert
It has a high risk for serious medication errors/adverse effects, so dose and route should be double-checked per policy.
What is naloxone
An opioid antidote.
What does naloxone reverse
Opioid-induced respiratory depression and sedation.
What can happen when naloxone is given to an opioid-dependent patient
Acute opioid withdrawal.
Why must you continue monitoring after naloxone
Naloxone may wear off before the opioid, causing respiratory depression to return.
Can one dose of naloxone always be enough
No. More doses may be needed.
What should happen even if naloxone works
The patient should still receive emergency medical evaluation because respiratory depression can return.
What is dexmedetomidine used for
Sedation, especially in ICU/intubated patients.
What are the TWO biggest side effects of Dexmedetomidine
Bradycardia + Hypotension.
What should the nurse continuously monitor for DEXMEDETOMIDINE (Precedex)
Heart rate and blood pressure/cardiac status.
How is dexmedetomidine given
IV infusion.
Can dexmedetomidine be given as an IV bolus
no
What medication should be available for significant bradycardia
Atropine.
What is propofol used for
General anesthesia and deep sedation, including ICU sedation.
What are the BIGGEST dangers of Propofol (Diprivan)
Respiratory depression/apnea + Hypotension.
What must be continuously monitored in PROPOFOL
Respirations, oxygen saturation, BP, and cardiac status.
Who should administer propofol
Personnel trained in airway management with continuous monitoring.
What serious problem can occur with prolonged high-dose propofol
Propofol infusion syndrome.
What is important about the propofol IV setup
Use strict aseptic technique because the lipid emulsion can support bacterial growth.
What is the BIGGEST danger of acetaminophen
LIVER DAMAGE.
What is the healthy adult maximum daily dose in the card
4 grams/day.
What should you check before giving acetaminophen
ALL sources of acetaminophen the patient is taking.
Why do you need to check cold/flu medications
They may secretly contain acetaminophen.
What is the antidote for acetaminophen overdose
Acetylcysteine.
What should patients avoid while taking acetaminophen
Excessive alcohol use.
What organ should you think about whenever you see acetaminophen
LIVER.