Chapter 7 Bipolar Disorders CLASS NOTES

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Antidepressant drugs: Tricyclics

A type of antidepressant that has been found to improve the condition of patients with depression significantly more than placebos.

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How do tricyclic antidepressants work?

They reduce depression by affecting neurotransmitter (NT) reuptake mechanisms.

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Selective Serotonin Reuptake Inhibitors (SSRIs)

A class of antidepressant drugs that act only on serotonin and include medications such as fluoxetine (Prozac) and sertraline (Zoloft).

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Ketamine-based drugs

Drugs that increase glutamate activity in the brain and may quickly alleviate depression, often used in combination with other drugs.