Cancer Treatments Based in Genetics

Flashcards covering cancer treatments based on genetics.

What are the three traditional cancer treatments mentioned?

Surgery, Chemotherapy, and Radiation

According to Dr. Funchain, what is the 'Holy Grail' of cancer treatment?

To kill the tumor once and for all with fewer side effects through genetic testing.

What is the primary goal of targeted therapy compared to conventional chemotherapy?

To only affect cancer cells.

What is molecular profiling used for in personalized cancer therapy?

Identifying prognostic markers and markers predictive of drug sensitivity/resistance and adverse events.

What is the function of Angiogenesis inhibitors?

Block new blood vessel formation.

What is the function of Proteasome inhibitors?

Cause cell death through disruption of function.

What is the function of Signal transduction inhibitors?

Disrupt cell signaling.

How does immunotherapy differ from traditional chemotherapy?

Immunotherapy unleashes the patient's own immune system to kill cancer cells, while chemotherapy uses drugs or radiation.

What are the two ways monoclonal antibodies are used in cancer treatment?

Marking cancer cells with an antigen or bringing cancer cells into close proximity to T cells for destruction.

What is CAR T-cell therapy?

Genetically modifying T-cells to bind a protein of interest.

What types of cancers is CAR T-cell therapy FDA approved for?

Blood and immune system cancers.

Name the three methods for targeted therapies

Small Molecule Drugs, Monoclonal Antibodies, and CAR T-cell therapy