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Enzymes
Proteins that act as critical catalysts to speed up thousands of different reactions in cells
Chemical reaction
A process in which one or more substances are changed into other substances
How does a chemical reaction work?
Molecules attaching to each other to form larger molecules or them breaking apart to form two or more smaller molecules
Metabolism
Sum total of all chemical reactions that occur within an organism
What are two general factors that govern the fate of a chemical reaction?
Direction and rate
Energy
The ability to do work or cause change
Kinetic energy
Energy associated with movement
Potential energy
Energy associated with structure or location
Chemical potential energy
Energy stored in atoms and in the bonds between atoms
Heat
Transfer of kinetic energy from one object to another or from an energy source to an object
Electrical / ion gradient
The movement of charge or the separation of charges can provide energy
First law of thermodynamics
States that energy cannot be created or destroyed
Second law of thermodynamics
Any energy transfer or transformation from one form to another increases the degree of disorder of a system. This is called entropy.
Entropy
The degree of disorder in a system. When energy is transferred some becomes unusable. Especially the more transfer there is.
Enthalpy
The total energy of a system
Free energy
The amount of energy in a system that can do work
Exergonic reaction
Reactions that release free energy and occur spontaneously.
Endergonic reaction
Reactions that require an addition of free energy and do not proceed spontaneously
adenosine triphosphate (ATP)
Primary energy currency of cells, providing energy for various biological processes
Hydrolysis
Chemical breakdown of a compound due to a reaction with water
Hydrolysis removes a phosphate group from ATP to make what?
adenosine diphosphate (ADP)
What does it mean that ATP is a cyclic molecule?
Loses a phosphate group, becoming ADP, which can be phosphorylated back to ATP in an endergonic reaction. Essentially a single ATP can be reused.
How many cycles a day does the average ATP go through?
10,000 cycles
Catalyst
Speed up the rate of chemical reactions without being consumed by the reaction
Biological catalysts include
Enzymes and ribozymes
Activation energy
Initial input of energy needed to start a chemical reaction
Collision theory
Reactants must collide with enough energy and in the correct orientation to achieve transition state
What are are common ways to overcome activation energy?
Heat and catalysts