ANTIVIRALS

Acyclovir

Zovirax, Sitavig, Avaclyr — Antiviral

Acyclovir PO/Function/Common Use

PO, IV, DERM — Inhibits susceptible virus replication — Herpes viruses

Acyclovir Adverse Drug Reactions/Special Considerations

Neuropsychiatric effects in children and young adults — Nausea, vomiting, diarrhea — May be used more often during viral outbreak

Valacyclovir

Valtrex — Antiviral

Valacyclovir PO/Function/Common Use

PO — Inhibits susceptible virus replication — Herpes viruses

Valacyclovir Adverse Drug Reactions/Special Considerations

— Nausea, vomiting, diarrhea — May be used more often during viral outbreak

Oseltamivir

Tamiflu — Neuraminidase inhibitor

Oseltamivir PO/Function/Common Use

PO — Inhibits susceptible virus replication — Influenza ("flu")

Oseltamivir Adverse Drug Reactions/Special Considerations

— Nausea, vomiting, diarrhea — Should take within 48 hours of symptom onset

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF)

Truvada — Antiretrovirals

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF) PO/Function/Common Use

PO — Inhibits susceptible HIV virus replication — HIV prophylaxis

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF) Adverse Drug Reactions/Special Considerations

Worsening hepatitis B virus infection when stopping — Nausea, vomiting, diarrhea — Can take the 2-1-1 regimen for prevention

Emtricitabine (FTC) + tenofovir alafenamide (TAF)

Descovy — Antiretrovirals

Emtricitabine (FTC) + tenofovir alafenamide (TAF) PO/Function/Common Use

PO — Inhibits susceptible HIV virus replication — HIV prophylaxis

Emtricitabine (FTC) + tenofovir alafenamide (TAF) Adverse Drug Reactions/Special Considerations

Worsening hepatitis B virus infection when stopping — Nausea, vomiting, diarrhea — CANNOT take the 2-1-1 regimen for prevention

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF) + bictegravir

Biktarvy — Antiretrovirals

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF) + bictegravir PO/Function/Common Use

PO — Inhibits susceptible HIV virus replication — HIV treatment

Emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF) + bictegravir Adverse Drug Reactions/Special Considerations

Worsening hepatitis B virus infection when stopping — Nausea, vomiting, diarrhea — Commonly used for a variety of patients

Entecavir

Baraclude — Antiviral

Entecavir PO/Function/Common Use

PO — Inhibits susceptible hepatitis B virus (HBV) replication — HBV treatment

Entecavir Adverse Drug Reactions/Special Considerations

Worsening hepatitis B virus infection when stopping — Nausea, vomiting, diarrhea — No special considerations

Sofosbuvir + velpatasvir

Epclusa — Antiviral

Sofosbuvir + velpatasvir PO/Function/Common Use

PO — Inhibits susceptible hepatitis C virus (HCV) replication — HCV treatment

Sofosbuvir + velpatasvir Adverse Drug Reactions/Special Considerations

— Nausea, vomiting, diarrhea — 8–12 weeks of treatment can cause sustained virologic response (SVR)