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What is hypovolaemia?
fluid lost quickly from intravascular space
results in hypoperfusion
results in inadequate delivery of oxygen and nutrients to cells
causes shock
hypoperfusion
inadequate tissue perfusion
What is dehydration?
fluid lost slowly from extravascular space (in cells)
What are the physiological consequences of hypovolaemia?
blood loss
reduced pre-load
reduced stroke vol
decreased CO
vasoconstriction & tachycardia
maintenance of blood pressure to vital organs
changes in mucous membrane colour (pale) and CRT
CRT
capillary refill time
What components should you assess a patient for to get information about their intravascular volume status (for hypovolaemia)?
HR
pulse quality
mucous membrnae colour
CRT
BP
mentation
temp
Normal HR for dogs (bpm)
70-140
HR in mild shock (compensatory) (bpm)
130-150
HR in moderate shock (bpm)
150-170
HR in severe shock (decompensatory) (bpm)
170-220
What is the normal colour of mucous membranes?
pink
What is the colour of the mucous membranes in an animal with mild shock?
normal to pinker
What is the colour of the mucous membranes in an animal with moderate shock?
pale pink
What is the colour of the mucous membranes in an animal with severe shock (decompensatory)?
pale pink - white
What is the normal CRT?
<2sec
What is the CRT of an animal with mild shock (compensatory)?
<1sec
What is the CRT of an animal with moderate shock?
2sec
What is the CRT of an animal with severe shock (decompensatory)?
>2sec
What the pulse quality of a patient with mild shock (compensatory) like?
bounding
What is the pulse quality of a patient with moderate shock like?
weak
What is the pulse quality of a patient with severe shock (decompensatory)?
very weak
What is the normal systolic BP (mmHg)?
>90
What is the systolic BP (mmHg) for a patient in mild shock (compensatory)?
>90
What is the systolic BP (mmHg) for a patient in moderate shock?
>90
What is the systolic BP (mmHg) for a patient in severe shock (decompensatory)?
>90
At what level of shock does mentation begin to get obtunded?
moderate
What components of your triage/physical exam will give you information about the patient’s extravascular volume status (for dehydration)?
moistness of mucous membranes
skin turgor
weight
globe position
urine output
severe dehydration → signs of hypovolaemia
How does dehydration impact urine output?
more concentrated = stronger colour
What can complicate patient assessment of hypovolaemia?
species variation (e.g. blue tongue of chow chow, cold ambient temp)
What are the physical exam findings of a patient with <5% body weight dehydration?
not clinically detectable
suspected from clinical history
What are the physical exam findings of a patient with 5-6% body weight dehydration?
tacky mucous membranes
minor delay in skin tent return
What are the physical exam findings of a patient with 6-8% body weight dehydration?
dry mucous membranes
mild to moderate delay in skin tent return
What are the physical exam findings of a patient with 8-10% body weight dehydration?
dry mucous membranes
marked delay in skin tent return
retracted globes within orbits
What are the physical exam findings of a patient with >10-12% body weight dehydration?
dry mucous membranes
persistent skin tent
dull corneas
retracted globes within orbits
evidence of hypovolaemia
What are the physical exam findings of a patient with >12% body weight dehydration?
hypovolaemic shock
death
At what %dehydration would you see hypovolaemic shock or death?
>12%
What can complicate patient assessment for dehydration?
hypersalivation
amount of subcut fat
skin‘s collagen content
What parameters from haematology, biochemistry and urinalysis may be affected by a patient’s hydration status?
PCV/TS
urea & creatinine
USG
PCV
packed cell volume
TS
total solids
USG
urine specific gravity
What type of assessment does patient assessment of dehydration/hypovolaemia need to be?
global assessment
What’s meant by a ‘global assessment’?
no single physical exam finding/clinicopathological parameter should be interpreted in isolation
Are patients with hypovolaemia ever stable?
NO
How do you administer fluids to a patient with hypovolaemia?
rapid fluid resuscitation of patient
large boluses of fluid (large volumes of fluid over a short period of time)
How do you administer fluids to a patient without hypovolaemia?
check for extravascular fluid losses
if present these should be corrected slowly (after 24/48hr time period)

a 20kg, 1yr 6m FN Labrador Retriever
spayed this morning
3hrs following surgery, your nurse notices blood dripping from the patient’s abdominal incision
Does this patient need fluids?
maybe
a 20kg, 1yr 6m FN Labrador Retriever
spayed this morning
3hrs following surgery, your nurse notices blood dripping from the patient’s abdominal incision
What will you assess Misty for first: dehydration or hypovolaemia?
hypovolaemia
a 20kg, 1yr 6m FN Labrador Retriever
spayed this morning
3hrs following surgery, your nurse notices blood dripping from the patient’s abdominal incision
You assess Misty for Hypovolaemia, and you find that she is QAR, has a HR of 150bpm, pale mucous membranes, a CRT of 2 seconds and reduced pulse quality. Is misty hypovolaemic?
YES
QAR
quiet alert responsive
a 20kg, 1yr 6m FN Labrador Retriever
spayed this morning
3hrs following surgery, your nurse notices blood dripping from the patient’s abdominal incision
You assess Misty for Hypovolaemia, and you find that she is QAR, has a HR of 150bpm, pale mucous membranes, a CRT of 2 seconds and reduced pulse quality.
How can fluids be used to stabilise misty?
give a rapid fluid bolus to restore the patient’s intravascular fluid volume
a 20kg, 1yr 6m FN Labrador Retriever
spayed this morning
3hrs following surgery, your nurse notices blood dripping from the patient’s abdominal incision
You assess Misty for dehydration, and you find that her mucous membranes are moist, she has no delay in skin tent and there is no change in her globe position within the orbit.
Is misty dehyrdated?
no
fluid requirement (ml) =
extravascular fluid deficit (ml) + maintenance requirements (ml) + ongoing loss (ml)
What’s an example of an ‘ongoing loss’
vomiting/diarrhoea
extravascular fluid deficit (ml) =
%dehydration x body weight (kg) x 10
maintenance requirements
rate of fluid needed to maintain a neutral fluid balance
What do ‘maintenance requirements’ replace losses from?
urination
respiration
sweating
defecation
What is the value of the maintenance requirement?
2ml/kg/hr
What do ‘maintenance requirements’ vary according to?
age
environment
exercise
diet
disease
How do you work out ongoing losses?
sometimes measured
visually estimated
hypervolaemia
aka fluid overload, medical condition where there’s too much fluid in the body
shock
a state of cellular and tissue hypoxia, most commonly caused by hypoperfusion
oncotic pressure
form of osmotic pressure induced by proteins (e.g. albumin) in a blood vessel’s plasma (blood/liquid)
normovolaemia
normal blood volume