PREPARATION 3 ASPIRIN CAPSULES Pt 2

SOFT GELATIN CAPSULES (pearls) characteristics:

contains more moisture

SOFT GELATIN CAPSULES (pearls) characteristics:

oblong, oval or round

SOFT GELATIN CAPSULES (pearls) characteristics:

elegant

SOFT GELATIN CAPSULES (pearls) characteristics:

single color or two-tone

SOFT GELATIN CAPSULES (pearls) characteristics:

with identifying markings

SOFT GELATIN CAPSULES (pearls) characteristics:

easily swallowed

SOFT GELATIN CAPSULES (pearls) uses:

to encapsulate and hermetically seal

SOFT GELATIN CAPSULES (pearls) uses:

liquids

SOFT GELATIN CAPSULES (pearls) uses:

dry powders

SOFT GELATIN CAPSULES (pearls) uses:

suspensions

SOFT GELATIN CAPSULES (pearls) uses:

preformed tablets

SOFT GELATIN CAPSULES (pearls) uses:

pasty materials

Digoxin (Lanoxicap)

Vit. A & E

SOFT GELATIN CAPSULES (pearls) drugs commercially prepared: 2

15 grains

000

10 grains

00

7.5 grains

0

5 grains

1

4 grains

2

3 grains

3

2 grains

4

1 grains

5

ASPIRIN CAPSULES Method 1

Triturate the powder

ASPIRIN CAPSULES Method 2

Choose the correct capsule size based on the

bottle

ASPIRIN CAPSULES Method 3

Separate the capsule body from the cap

ASPIRIN CAPSULES Method 4

Fill the capsule shell (punch method, rolling)

ASPIRIN CAPSULES Method 5

Sealing, weighing the prepared capsule to check if

it has the right amount

ASPIRIN CAPSULES Method 6

Cleaning and polishing (clean with gauze; polish

with mineral oil)

clean with gauze

how to clean aspirin capsules

polish with mineral oil

how to polish aspirin capsules

C9H8O4

Benzoic acid

Acetylsalicylic acid (ASA)

3-acetyl

Acetaminophen

ASPIRIN CAPSULES Synonyms

ASPIRIN CAPSULES Synonyms

C9H8O4

ASPIRIN CAPSULES Synonyms

Benzoic acid

ASPIRIN CAPSULES Synonyms

Acetylsalicylic acid (ASA)

ASPIRIN CAPSULES Synonyms

3-acetyl

ASPIRIN CAPSULES Synonyms

Acetaminophen

ASPIRIN CAPSULES Description of Final Product

HGC containing white,

odorless powder

ASPIRIN CAPSULES Description of Final Product

ASA capsule contain NLT

93.0% and NMT 107% of the

label amount of aspirin

93.0%

ASA capsule contain NLT

_ and NMT 107% of the

label amount of aspirin

107%

ASA capsule contain NLT

93.0% and NMT _ of the

label amount of aspirin

ASPIRIN CAPSULES Uses

analgesic

ASPIRIN CAPSULES Uses

antipyretic and anti-inflammatory

ASPIRIN CAPSULES Uses

prevention of transient ischemic

attack

ASPIRIN CAPSULES Uses

prophylaxis & thromboembolic

disorders

ASPIRIN CAPSULES Uses

reduces also fever and cold

ASPIRIN CAPSULES Procedure 1

Know the capsule size

ASPIRIN CAPSULES Procedure 2

Weigh the needed amount of

ingredient

ASPIRIN CAPSULES Procedure 3

Triturate the powder

ASPIRIN CAPSULES Procedure 4

Separate the cap and body of

the capsules

ASPIRIN CAPSULES Procedure 5

Put the powder on the pill tile

ASPIRIN CAPSULES Procedure 6

Block and Divide

ASPIRIN CAPSULES Procedure 7

Fill the capsule using – “Punch

Method”

ASPIRIN CAPSULES Procedure 8

Seal the capsule

ASPIRIN CAPSULES Procedure 9

Clean & Polish the capsule

using tissue paper with very

small amount mineral oil

ASPIRIN CAPSULES Procedure 10

Insert a cotton plug into

the container

Official white label

ASPIRIN CAPSULES Label

30 mL wide mouth amber bottle

ASPIRIN CAPSULES Container

ASPIRIN CAPSULES Remarks

The method used was punch

method

ASPIRIN CAPSULES Remarks

Cotton was used to absorb

moisture

ASPIRIN CAPSULES Remarks

The pharmaceutical dosage

form is a capsule