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What is the primary role of the cori cycle?
To convert lactate back to glucose in the liver
Chronic excessive cortisol may result in ____?
Reductions muscle size
Which of the following processes is directly responsible for the majority of ATP Production in the cell?
Oxidative Phosphorylation
T or F, oxygen consumption is a very good indicator of beta-oxidation?
False, oxygen consumption is a good indicator of energy expenditure
What is the primary storage form of fats in the body?
Triglycerides
Where does beta-oxidation occur within the cell?
Mitchondria
The term “complex carbohydrate” describes dietary _____.
Starch
How does exercise affect insulin action?
Increases insulin sensitivity
The CNS relies predominantly on which energy substrate?
Glucose
T or F, During exercise, triglycerides are mobilized from adipocytes, the liver, or the muscle. enter the blood stream as free fatty acids and are metabolized into acetyl CoA molecules through the process of oxidative phosphorylation.
True
What is the primary input for the TCA cycle?
Acetyl-CoA
How long does the ATP-PC system normally last?
10-15 seconds
Why may RER be greater then 1?
Bicarbonate buffers the acidic environment, resulting in additional carbon dioxide
A distance track athlete is training. Which of the following workouts will result in the greatest EPOC for this individual?
Running intervals of 3 mins at faster than a race pace followed by 1 min rest, then repeat
which of the following is not a by-product of the citric acid cycle?
Pyruvate
What is the thermic effect of food?
The energy it takes to digest and process food
T or F, Exercise training decreases intramuscular lipid content for more efficient utilization of fatty acids during low/moderate intensity exercise?
False, exercise training increases intramuscular lipid content.
An activity lasting 90 seconds would rely predominantly on which energy system?
Fast glycolysis
Which of the following statements about the thermic effect of food is true?
TEF is higher for proteins than for carbohydrates
What is the primary reason for the increased energy expenditure in cold climates?
Increased energy required to maintain body temperature
What is the primary mechanism by which physical activity increases total daily energy expenditure?
By increases energy expenditure from activity
What is the process of glycogen synthesis form glucose called?
Glucogenesis
What is the process of breaking down triglycerides into fatty acids and glycerol called?
Lypolysis
T or F, Pyruvate is converted to Acetyl-CoA enter the citric acid cycle to generate NADH, FADH2, and ATP?
True
Anabolic processes _____ energy, while catabolic processes _____ energy.
Require, release
What is the role of glucagon-like peptide-1 agonists in diabetes management?
increase insulin sensitivity
The process of the liver converting lactate to glycogen is called?
Cori cycle
T or F, Pyruvate is converted to Acetyl-CoA to enter the citric acid cycle to generate malate
False, is generates NADH, ATP, FADH2
Which of the following contributes the most to basal metabolic rate during rest?
Liver
After a marathon race an individual has drained glycogen supplies to initiate _____ the individual should consume a carb rich meal?
Glucogenesis
T or F, Glycolysis occurs in the mitochondria in order to generate ATP, NADH, and Pyruvate?
False, glycolysis occurs into the cytosol of the cell.
T or False, As the intensity of an exercise increases, utilization of lipids as an energy source increases?
False, the energy source moves to carbs
_____ is the largest contributor to overall energy expenditure during rest?
Resting metabolic rate
During prolonged low-intensity exercise, _____ serves as the main energy substrate throughout exercise?
Fat
Which of the following is used to assess bone mineral content and osteoporosis?
DXA
When does most protein synthesis occur?
After exercise
What is the end product of glycolysis under anaerobic conditions?
Lactate
When hormone is released in response to stress and promotes gluconeogenesis?
Cortisol
A low intensity activity lasting 60 min would rely predominantly on which energy system?
Beta-oxidation
Obesity is classified as a BMI greater than?
30
_____ is the second most abundant nutrient in the body next to water?
Protein
Which of these is a storage site for glycogen?
Liver
What does the term EPOC stand for in exercise physiology?
Excess Post-exercise Oxygen Consumption
_____ is essential fat for men whereas _____ is essential fat for women?
3% and 12%
What is the net gain of ATP from one molecule of glucose through anaerobic glycolysis?
2 ATP
How does exercise training impact the utilization of energy systems?
It enhances the capacity of aerobic metabolism
Which of the following is a key enzyme in the ATP-PC system?
Creatine kinase
T or F, Accumulation of AMP occurs when the ATP-PC system becomes depleted. This accumulation of AMP helps facilitate glucose entering the cell to initiate glycolysis.
True
Carbohydrates are classified as all of the following except:
gluconeogenesis
What is the primary reason for the higher thermic effect of protein compared to carbohydrates and fats?
Protein requires more energy for digestion and absorption
How many molecules of NADH are produced per glucose molecule during glycolysis?
2 NADH
Which macromolecule is not stored in the body?
Protein
Which macromolecule provides the most energy per gram?
Fats
What is the main function of the electron transport chain?
To generate a proton gradient for ATP synthesis
Which of the following is a disaccharide?
Sucrose
True or False, if False select why the following statement is false. Accumulation of AMP occurs when the ATP-PC system becomes depleted. This accumulation of AMP helps facilitate lipids entering the cell to initiate beta-oxidation
False, the accumulation of AMP facilitates glucose entering the cell to initiate glycolysis
What does RER stand for in exercise physiology?
Respiratory Exchange Ratio
A “health guru” is selling a new diet pill that “stops your body from storing sugar” (e.g. stops glycogen storage). Answer the following question based on that information. What process will initiate if the body can no longer store sugar (ie glucose) and the brain needs glucose?
Gluconeogenesis
Gluconeogenesis would occur under which of these situations?
Intense physical activity without sufficient carbohydrate intake
How does pregnancy affect energy expenditure?
Increases energy expenditure
With detraining oxygen deficit_____
Increases
What is the role of glucagon-like peptides (GLP-1)?
Increase insulin secretion
What percentage of Total Daily Energy Expenditure (TDEE) is typically attributed to the thermic effect of food?
5-10%
What is the primary role of ghrelin?
Increase hunger
Which of the following factors can lead to an increase in Excess Post-exercise Oxygen Consumption (EPOC)?
High-intensity exercise
Which of the following is NOT a by-product of glycolysis?
FADH2
Which of the following processes is responsible for the synthesis of fatty acids from acetyl-CoA?
Lipogenesis
What is the primary function of IGF-1 in muscle cells?
Activate protein synthesis
Which of the following best describes the role of titin in muscle contraction?
It provides structural support and elasticity
Which signaling pathway is promarily responsible for muscle protein synthesis?
mTOR pathway
What happens to the diaphragm during inhalation
It contracts and moves down
What is the primary function of skeletal muscle?
Movement and support
T or F, Excitation-Contraction coupling an action potential travels down the motor neuron thich cause the release of acetyl choline into the neuromuscular junction?
True
What type of muscle contraction involves muscle shortening?
Concentric
What is the main regulator of protein synthesis?
mTOR
T or F, Calcium binds with troponin to allow for the conformational change of the complex and opening the titin/actin binding site
False, it opens the Myosin/actin binding site
What is the primary function of the motor unit in muscle contractions?
Transmit AP form the nerve to the muscle
What type of muscle contraction is most associated with muscle damage and subsequent hypertrophy
Eccentric
Which best describes the length-tension relationship in muscle contraction?
greatest force is produced when at an intermediate length
Which training would allow for increased muscular power?
Jump training with low volume
Primary effect of exercise training on the lactate threshold and what does this mean?
Increases threshold, meaning an individual can exercise at a higher intensity without accumulating lactate
_____ muscles tend to have a faster twitch speed compared to _____ muscles?
Fusiform, pennated
Primary role of satellite cells in the muscle adaptation to exercise?
aid in muscle repair and growth
Maximal ventilatory volume is the product of?
Breathing rate and tidal volume
As exercise intensity increases _____ increases
tidal volume
What is the primary effect of exercise training on the respirtory muscles?
No effect
After an AP has reached the neuromuscular junciton, an AP travels throughout the muscle to release _____ from the _____?
Calcium, SR
Primary effect of hyperventilation on blood pH
Increases blood pH
Muscle fibers that have high ATPase acdtivity for stronger contraction that fatigue quickly?
type IIX
What type of contraction occurs without a change in muscle length
Isometric
What is the primary function of the T-tubules in muscle cells?
Transmit AP into the muscle fiber
True or false, if false explain why. A powerstroke involves the hydrolysis of ATP by myosin to release energy to pull myosin filaments closer together.
False, actin filaments are pulled closer together
What is the primary function of the Z-line in a sarcomere?
Anchor actin filaments
The body requires __________ different amino acids.
20
The majority of protein synthesis occurs________
After exercise
True or false, if false explain why. Calcium binds with tropomyosin to allow for the conformational change of the troponin/tropomyosin complex and opening the actin:myosin binding site.
False, calcium binds with troponin
What is the primary function of the neuromuscular junction?
Transmit action potentials from the nerve to the muscle
Which of the following is a characteristic of Type IIx muscle fibers?
High glycolytic capacity
What are satellite cells?
Myogenic stem cells that aid in muscle repair and growth
What is the primary cause of delayed onset muscle soreness (DOMS)?
Eccentric contractions