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Which of the following is an example of natural passive immunity?
Vaccines
Antibodies
Response to Infection
Breastfeeding
None of the above
Breastfeeding
Which of the following is a way that a heightened body temperature helps combat foreign pathogens?
Increases cell metabolism
Causes pathogens to dissolve in the intense heat
Makes liver and spleen retain zinc to hinder bacterial growth
A and C
All of the above
A and C
Increases cell metabolism and Makes liver and spleen retain zinc to hinder bacterial growth
Which kind of antibiotic functions by binding to DNA enzymes, prohibiting DNA replication and mitosis
Penicillin
Erythromycin
Neomycin
Ciprofloxacin
None of the above
Ciprofloxacin
What is NOT a way for the cells of the innate immune system to know where to go in the body?
Pain
Swelling
Chemical signals like Histamine
Widening of blood vessels
None of the above
None of the above
What is NOT a way antibiotic resistance occurs?
Natural Selection
Gene Transfer
Mutation
None of the above
None of the above
Agglutination of soluble molecules typically causes them to…
Become insoluble and precipitate
Retain solubility and dissapate
Break down the antigens that are being agglutinated
Clump into smaller molecules for larger chance to be phygocytized
None of the above
A. Become insoluble and precipitate
Which of the following is NOT an external defense mechanism of the immune system?
Skin
Mucus
Sweat Glands
Sebum Glands
None of the above
None of the above
Which of the following are characteristics determining the stimulating of immune response by antigens?
Size
Shape
Complexity
A, B, and C
None of the above
A,B,C
Size
Shape
Complexity
Which of the answer choices describes why antibiotics are not effective against viruses as with bacteria?
Antibiotics target specific bacterial structures, such as the cell wall and components of protein synthesis, which are absent in viruses due to their capsid structure and reliance on host cell replication
The bacterial-specific processes of DNA replication as well as bacterial cell wall and protein synthesis are compatible with antibiotic resistance, thus, are not applicable to viruses
Viruses have sophisticated efflux pumps that expel antibiotics from their structure, resulting in the ineffectiveness of antibiotics in viral infection
A and B
All of the above
A and B
Which of the following cells are responsible for producing antibodies?
T Cells
Macrophages
B Cells
Natural killer cells
None of the above
B cells
Which of the following is an example of passive immunity?
Receiving a vaccine for measles
Developing antibodies after recovering from an illness
A baby acquires antibodies through breast milk
The production of antibodies by Memory B Cells
None of the above
A baby acquires antibodies through breast milk
Which of the following is the most abundant type of white blood cell?
NK cells
Phagocytes
Macrophages
Neutrophils
None of the above
Neutrophils
In a primary immune response, how long does it take for the body to respond to the antigen?
1-4 days
7-15 days
4-7 days
1-7 days
4-7 Days
Which of the following are ways an infection can be introduced to the immune system
Vaccinations
Exposure to pathogens in the environment
Prebiotics
Probiotics
All of the above
All of the above
What are these false feet called?
Killer T-Cell
Filopodia
Pseudopodia
Foraminifera
Lamellipodium
Pseudopodia
Which of the following is a difference between B-cell and T-cell clonal deletion?
B-cell clonal deletion originates in the red bone marrow, T-cell clonal deletion does not
B-cells that are not complementary to any autoantigen are released into the blood unlike T-cells
B-cells need to recognize an MHC in order to receive the survival signal
B-cell clonal deletion happens in the thymus
None of the above
B-cell clonal deletion originates in the red bone marrow, T-cell clonal deletion does not
Which of the classes of antibodies are the most prevalent?
IgE
IgD
IgA
IgG
IgM
IgG
Which of the following are secondary lymphoid organs?
Thymus
Red Bone Marrow
Lymph Nodes
A and C
All of the above
Lymph Nodes
Which cytokine inhibits the spread of viral infections
Interleukins
Interferons
Growth factors
Tumor Necrosis Factors
Chemokines
Interferons
What do interleukins do?
Link immune cells together
Stimulate movement of immune cells
Attack infectious agents
Send signals between immune cells
Stimulate division of immune cells
Send signals between immune cells
Which of the following is a primary function of the macrophage?
Repairing damaged cell tissue
Responding to allergens
Remembering information about pathogens
Phagocytizing pathogenic organisms
None of the above
Phagocytizing pathogenic organism
In which of the following structures do B-Lymphocytes mature in
Spleen
Red Bone Marrow
Tonsils
Lymph nodes
None of the above
Red Bone Marrow
If your white blood cells are overwhelmed with fighting off pathogens, what is most likely to happen?
They commit mass apoptosis
Gametes enter the bloodstream to assist the white blood cells
Chemicals are released to signal for a fever
Your brain signals swelling of your whole arm
None of the above
Chemicals are released to signal for a fever
Which of the following do NOT induce a fever in the body
Interleukin
Prostaglandin
Cytokinetic B-antibodies
Tumor necrosis factors
None of the above, all induce a fever
Cytokinetic B-antibodies
How many heavy chains does an immunoglobulin have?
2
3
0
1
4
2
Interferons are proteins produced by what?
NK cells
MAST cells
Macrophages
Cells that respond to stimuli
Neutrophils
Cells that respond to stimuli
Which of the following is NOT a class of antibodies?
IgB
IgA
IgE
IgD
IgM
IgB
Which class of antibody is the most common and long-lasting?
IgM
IgG
IgA
IgE
IgD
IgG
How many interleukins have scientists currently identified?
30
32
35
37
40
35
T/F IgG is the most prevalent antibody in the blood
True
T/F The thymus is the most important organ in the secondary immune system
False
Antigens are protein receptors found on B-Cells which play a crucial role in immune response
False
T/F After someone is exposed to a particular antigen and undergoes a primary immune response, they will never experience symptoms of sickness again from that antigen
False
T/F When white blood cells and macrophages are overwhelmed they produce pyrogen chemicals that cause fever and faster metabolisms
True
T/F Antigens are produced by the body and can attach to antibodies to neutralize and signal the lysis of the antibody
False
T/F The transfer of IgG antibodies from the mother to the fetus by FcRn receptors syncytiotrophoblast cells through the placenta is an example of active immunity
False
T/F The innate immune system provides specific responses to particular pathogens
False
T/F The chemokines are chemotactic
True
T/F Tumor Necrosis Factors are secreted by B-cells
False, usually macrophages
T/F A high neutrophil count signals that you are healthy
False
T/F Neutrophils don’t self-destruct after destroying an antigen
False
T/F Lymph and blood differ in the direction they circulate the body
True
T/F Apoptosis is uncontrolled cell suicide
False, Necrosis is uncontrolled cell suicide
T/F Monocytes are the largest lymphocytes
True
T/F: Remembering cells are a form of protection for the body.
True
T/F: T cells mature in the thymus
True
T/F B Cells mature in the thymus
False, they mature in the bone marrow
T/F IgM is the least prevalent antibodies
False, usually IgE a the least prevalent
T/F: Histamine white blood cells release basophils to fight allergens.
False, other way around
T/F: Basophils are the largest type of white blood cells.
True
T/F: Penicillin works by breaking down bacterial cell walls, killing the bacteria
True
T/F Vaccines are a form of active immunity
True
T/F Antibiotics work by attaching themselves to a bacteria’s cell wall to prevent it from spreading
True
FRQ How is the immune system different from other body systems
It’s a collection of different organs that have a common function and is easily adaptable
FRQ What kind of response will the next infection be if you’ve been infected once? What does the timeline for that look like?
Your next infection will be a secondary infection. You will be cured faster because your antibodies will be ready to fight earlier
FRQ What is the function of a Basophil? Which types of infections/reactions does it specifically deal with?
Defend from infections in the body and protect the body. It specifically deals with parasites
FRQ Compare neutrophils and macrophages. What is a key difference between the two?
FRQ Which of the external barriers of the immune system is the most important for preventing disease in your opinion?
FRQ How do antibodies work in the fight against pathogens and lead to the agglutination of pathogens?
Antibodies will bind to the binding sites of the pathogen so that they cannot bind to the targets. The antibodies connect and clump together.
FRQ How does EBV attack White Blood cells? What Blood cells does it target?
EBV targets the B-Lymphocytes. After infecting the B-lymphocytes, EBC prevents the cell from committing apoptosis and ventures to infect Memory B-cells
FRQ Explain how the vaccine prepares the immune system to fight a specific pathogen
A vaccine introduces a weakened or inactivated form of the pathogen, or a part of it into the body. This triggers the production of memory B and T cells without causing illness. If the real pathogen enters the body in the future, these memory cells recognize it and initiate a faster and stronger immune response.
FRQ What is the role of B and T lymphocytes? How are they different and similar?
They are both white blood cells that are a part of the immune response system of the body. B lymphocytes come from bone marrow while T lymphocytes come from the thymus. B cells produce antibodies that help neutralize viruses and pathogens. T cells destroy pathogens and help communicate with the immune system to stimulate and control the response.
FRQ What is the relationship between antibodies and antigens
FRQ What’s the difference between the primary and secondary immune response. List TWO examples
FRQ Describe the role of macrophages in the immune response
FRQ Explain the role of the thymus in the production of T-cells
The thymus is the site of production and maturation of T-cells.
FRQ What’s the difference between active and passive immunity. List some examples of each
Passive immunity is when a person is introduced to antibodies instead of developing them on their own through combating a pathogen. An example of passive immunity is when infants are passed on antibodies from their mothers through the placenta. Passive immunity takes less time to develop, but is temporary. Active immunity, on the other hand, is acquired through the body combating a antigen and developing its own antibodies for it, such as a person gaining COVID-19 immunity through being sick with the virus. This immunity can be natural or vaccine-induced, and takes a while to develop but is long-lasting.
FRQ Explain how antibiotic resistance occurs
When a person doesn’t finish a full course of antibiotics, they allow for the strongest/ fittest cells to survive and reproduce which makes them hosts to cells that can’t be killed by antibiotics
FRQ What is the importance of one marrow
Bone marrow is home to stem cells which have the ability to become any type of cell, most importantly, red blood cells which play a crucial role in the immune system
FRQ Compare and contrast B-cell receptors (BCRs) and antibodies
BCRs and antibodies are both immunoglobulins. However, they attach to cells in different ways. BCRs are membrane-bound by a transmembrane tail. Antibodies lack both of those distinctive characteristics, and are instead soluble
FRQ What are the three types of antigens? Distinguish the differences between them.
The three types include exogenous, endogenous, and autoantigens. Exogenous antigens include toxins and other secretions and components of microbial cell walls, membranes, flagella, and pilli. Endogenous antigens: includes protozoa, fungi, bacteria, and viruses that reproduce inside a body’s cells to produce endogenous antigens. Autoantigens are antigenic molecules derived from normal cellular processes.