1 - STRUCTURE AND FUNCTIONS OF CELL MEMBRANES

0.0(0)
studied byStudied by 0 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/17

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

18 Terms

1
New cards

Lipids in cellular membranes

Phospholipids, Glycosphingolipids, and cholesterol

2
New cards

Function of lipids in cellular membranes (3)

  1. Glycosphingolipids: Cell recognition and signaling.

  2. Cholesterol: Membrane fluidity and raft formation

3
New cards

Lipids of outer leaflet

(Phosphatidyl) choline, sphingomyelin, and glycosphingolipids

4
New cards

Lipids of inner leaflet

(Phosphotidyl) Serine, Ethanolamine, and inositol

5
New cards

Membrane fluidity

Lateral movement

6
New cards

Types of membrane fluidity (2)

  1. Lateral diffusion

  2. Flip-flop (Transverse diffusion)

7
New cards

Lateral diffusion

Rapid, within same leafelet

8
New cards

Flip-flop (Transverse diffusion)

Slow, one leafelet to another

9
New cards

Factors of Membrane fluidity

Ratio of saturated to unsaturated fatty acids and cholesterol content

10
New cards

Enzymes that assist with phospholipid translocation (3)

  1. Flippases

  2. Floppases

  3. Scrablases

11
New cards

Flippases

Use ATP to move phosphatidylethanolamine and phosphatidylserine from the outer to the inner leaflet

12
New cards

Floppases

Use ATP to move phospholipids like phosphatidylcholine and sphingolipids from the inner to the outer leaflet.

13
New cards

Scrablases

Move phospholipids down their concentration gradient, disrupting membrane asymmetry and signaling apoptosis.

14
New cards

Saturated fatty acids effects on fluidity

packed tightly, decreasing membrane fluidity. At room temperature, they are solid.

15
New cards

Unsaturated fatty acids effects on fluidity

increase membrane fluidity due to their kinked structure, which prevents tight packing.

16
New cards

Cholesterol effect on fluidity

Makes saturated regions less fluid and unsaturated regions more fluid. It also broadens temperature range

17
New cards

Lipid rafts

Domains of sat. FA, cholesterol, and proteins. Help with signals, curvature, and interactions

18
New cards

Fluid Mosaic Model

Describes the membrane as a dynamic bilayer of amphipathic lipids with embedded proteins that can move laterally. It emphasizes fluidity, diversity, and functionality.