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Why must the epinephrine response be terminated quickly?
The fight-or-flight response must stop once the threat is gone
How does signaling stop at the receptor?
The ligand diffuses away and the receptor becomes unbound
What happens to the G protein during termination?
It drops the phosphate and binds GDP, becoming inactive
How is cAMP signaling stopped?
Adenylyl cyclase stops producing cAMP
What role do protein phosphatases play?
They remove phosphates and deactivate kinases
What happens to glycogen phosphorylase?
It stops hydrolyzing glycogen and blood glucose normalizes