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Nasal placodes invaginate to form nasal pits at what week?
5th week
Two prominences surrounding the nasal pits
Lateral nasal prominence (outer edge), medial nasal prominence (inner edge)
Which prominence does NOT contribute to the upper lip
Lateral nasal prominence
What forms the upper lip
Fusion of the two medial nasal prominences with the maxillary prominences
What forms the lower lip and jaw
Mandibular prominences merging across the midline
Five facial prominences that form the nose
Frontal prominence (bridge), 2 medial nasal prominences (crest/tip), 2 lateral nasal prominences (alae)
Intermaxillary segment - three components
Labial component (philtrum), upper jaw component (4 incisors), palatal component (primary palate)
What is the intermaxillary segment continuous with
Rostral portion of the nasal septum (from frontal prominence)
Week the palatine shelves first appear
6th week
Stage 1 of secondary palate fusion
Lateral differentiation of palatine shelves, directed obliquely downward beside tongue
Stage 2 of secondary palate fusion
7th week - tongue moves downward, shelves ascend to horizontal position
Stage 3 of secondary palate fusion
Lateral growth of the shelves
Stage 4 of secondary palate fusion
Creation of epithelial wall
Stage 5 of secondary palate fusion
Fusion of shelves ~1/3 of the way back, proceeds anterior to posterior
Landmark between primary and secondary palate
Incisive foramen
Week of intramembranous ossification of the palate
8th week I.U.
Ossification centers for the fused lateral palatal shelves
Trabeculae from primary ossification centers of each palatine bone
Where does ossification NOT occur in the palate
Most posterior part - becomes the soft palate
Branchial arches supplying soft palate musculature
First, second, and fourth arches
Week the midpalatal sutural structure becomes evident
10.5 weeks
Fetal palate growth pattern 7-18 weeks
Length increases faster than width
Fetal palate growth pattern after 18 weeks
Width increases faster than length (midpalatal suture + appositional growth)
Least severe form of cleft palate
Bifid uvula
Maxilla body - what cavity does it contain
Maxillary sinus (antrum of Highmore)
Four surfaces of the body of the maxilla
Anterior, posterior/infratemporal, superior/orbital, medial/nasal
Four processes of the maxilla
Zygomatic, frontal, alveolar, palatine
Shape and description of the palatine bones
Irregularly shaped, L-shaped bones
What do the palatine bones form
Posterior hard palate, lateral wall of nasal fossa (between medial pterygoid plate and maxilla), posterior floor of orbit
What separates nasal cavity from oral cavity posteriorly
Horizontal plates of the palatine bones
Three postnatal growth directions of the maxilla
Vertical, horizontal, transversal
Two mechanisms producing vertical (downward) growth of maxilla
Sutural displacement of the whole nasomaxillary complex, and remodeling (resorption/deposition)
Proportion of downward maxillary arch movement from sutural displacement
About half
Bone surface pattern in vertical maxillary growth
Deposition on downward-facing surfaces, resorption on superior-facing surfaces
Two-part process of downward tooth movement
a to b: remodeling of alveolar bone (paced by periodontal membrane); b to c: displacement of maxilla as a whole (alveolar bone not participating)
Principal site of horizontal maxillary elongation
Maxillary tuberosity
Until what age does anterior bone deposition contribute to horizontal maxillary growth
5-6 years
What does posterior bone deposition at the tuberosity cause
Anterior displacement of the maxillary complex
Relationship between forward displacement and backward tuberosity growth
Extent of forward displacement is matched by amount of backward bone growth
What allows transversal (width) growth of the maxilla
Presence of the mid-palatal suture (open throughout growth)
Second contributor to maxillary width besides the suture
Remodeling of the palatal vault (resorption on nasal side, apposition on oral side)
Who studied maxillary growth using metallic implants
Bjork and Skieller
Maxillary width increase (bi-molar) from Bjork/Skieller implant study
+9.5 mm sutural component / total change measured across the arch
Growth site vs growth center - definition
Site = location where growth occurs; center = location of independent, genetically controlled growth
Are maxillary sutures growth centers or growth sites
Growth sites, NOT growth centers
What do maxillary sutures allow
Downward and forward positioning of the maxilla
"Push" theory of maxillary displacement - accepted or rejected
Rejected
"Sutural" theory of maxillary displacement - accepted or rejected
Rejected
Nasal septum theory of maxillary displacement - proposed by
Scott
Is there cartilage in the maxilla itself
No
Where is the cartilage that influences maxillary growth
Nasal septum
Type of ossification at the septo-ethmoidal junction
Endochondral ossification
Where is proliferation seen in septal cartilage
Vomeral edge of the cartilage
Bone activity pattern in the palatal area (nasal septum theory)
Resorption on nasal side, apposition on oral side of bony palate
Who proposed the Functional Matrix Theory
Melvin Moss
Core claim of Functional Matrix Theory
The bone does not regulate its own growth rate/direction; functional soft tissues are the actual governing determinant
What does Functional Matrix Theory explain vs not explain
Explains WHAT happens, not HOW it happens
Term for the functioning spaces around the maxilla/mandible per Moss
Orofacial capsular matrix
Per Moss, what enlarges to drive maxillary growth
Nasal and oral cavities (e.g., maxillary sinuses) in response to functional needs
Overall consensus on the driving mechanism of maxillary growth
Multifactorial process
Who conducted the Bolton-Brush Longitudinal Study on adult craniofacial growth
Behrents
Does craniofacial growth stop after adolescence
No - continues into adulthood
Three clinical fields a