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What are some factors that cause obesity
Genetics
Family reinforcement
Physiologic factors (growth periods, BMR, activity, lean muscle mass)
Psychological factors
Other environmental factors
What are some health risks of obesity
Pulmonary disease
Nonalcoholic fatter liver disease
Gallbladder disease
Gynecological abnormality
OA
Gout
Phlebitis
Cancer
Coronary heart disease (diabetes, hypertension, dyslipedmia)
How is metabolic syndrome diagnosed
Need at least 3 measures abnormal
Factors that lead to being diagnosed with metabolic syndrome
Waist circumference
Triglycerides
HDL
Blood pressure
Fasting glucose
Unhealthy waist circumference for metabolic syndrome
>40 inches for men
>35 inches for women
Unhealthy triglycerides for metabolic syndrome
>150 mg/dL
Unhealthy HDL for metabolic syndrome
Unhealthy BP for metabolic syndrome
>130 and/or >85 mm HG
Unhealthy fasting glucose for metabolic syndrome
> 100 mg/dL
What are some effects of excess lipids
Lipotoxicity
Lipid peroxidation
Lipotoxicity with excessive lipids
Lipid build up in non adipose, causing ER stress, inflammation, mitochondrial dysfunction and cell death
Lipotoxicity effects what structures
Pancreas
Heart
Kidneys
Liver and muscles
Lipid peroxidation with excessive lipids
Perodixeds of PUFA for due to COX, LOX, cytochrome P450s and free radicals
Lipid peroxidation affects what
Membrane structure and tigger inflammation, cancer, neurodegenerative disease, etc.
Most common weight loss surgery in US
Vertical sleeve gastrectomy
Diets associated with weight loss
High protein
Zone diet
Low calorie
Energy restricted lacto-ovo-vegetarian
Low carb (short term)
Low fat
Low glycemic load with energy restriction
Mediterranean diet with energy restriction
Moderate protein
High protein diet
(25% energy from protein, 30% from fat, 45% from carbs)
Zone diet
(40% carbs, 30% fat, 30% protein)
Moderate protein diet
(12% protein, 30% fat)
Steps in clinical practice guidelines for obesity treatment
1. Recognize as chronic disease and get permission
2. Assessment
3, discussion of treatment options
4. Agreement regarding goals of therapy
5. Follow up and advocacy
How do the FDA approve weight loss drugs work
A lot suppress the appetite or decrease fat absorption or burn fat, or increases satiety
What are some components of a sound weight management program
Dietary modification swap as to decrease energy intake
Changing food behavior by managing cures
Increase activity each week
What screening questionnaire is used for eating disorders
SCOFF
Describe the SCOFF screening for eating disorders
Do you make yourself feel SICK cause you feel uncomfortably full?
Do you worry you have lost CONTROL over how much you eat
Have you recency lost more than ONE stone (14lb) in a 3 month period
Do you believe yourself to be FAT when others say you are too thin
Would you say that FOOD dominates your life