Chapter 15: Marijuana
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24 Terms
Cannabis sativa, main ingredient is THC
What is marijuana? List and describe the three species.
The primary psychoactive agent, delta-9-tetrahy-drocannabinol.
By scraping or breaking off the tiny hairlike trichomes and packing them together, a more concentrated product called hashish can be made, with up to 65% THC by weight.
Growers have become expert at selecting particular strains and removing the male plants prior to pollination so that the female plants produce more flowers and no seeds
Describe the following Preparations from Cannabis:
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Wrote a book about the effects of cannabis, he called it the “Liberator of Sin.” He recommended it for some medical uses,
Who was Shen Nung and what role did he play in the history of marijuana?
served as the commissioner of the U.S. Bureau of Narcotics. Anslinger used his position to tout the dangers of marijuana and to lobby for federal legislation banning the use, sale, and trafficking of the drug. wrote an influential editorial entitled “Marijuana—Assassin of Youth.”
Who was Harry Anslinger and what role did he play in the history of marijuana?
The federal law did not outlaw Cannabis or its preparations; it just taxed the grower, distributor, seller, and buyer and made it, administratively, almost impossible for anyone to have anything to do with Cannabis.
Explain the Marijuana Tax Act of 1937.
asked the New York Academy of Medicine to study the effects of marijuana to determine whether the drug caused long-term damage to its users. Opposed the criminalization of marijuana and advocated for its medical usage.
Who was Fiorello LaGuardia and what role did he play in the history of marijuana?
Chemicals in marijuana, 70
What are cannabinoids and how many are found in the cannabis plant?
into the blood and distributed first to the brain, then redistributed to the rest of the body, so that within 30 minutes much is gone from the brain.
How is marijuana absorbed when smoked?
occur together, usually within 5 to 10 minutes.
When does the peak mood-altering and cardiovascular effects take place (smoked)?
THC half life: 19 hours Metabolites: 50 hours
What is the half-life of THC and its metabolites?
2-3 weeks
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90 minutes
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1992 discovery of a natural substance produced in the body that has marijuana-like effects when administered to animals.
What is anandamide, explain?
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What is Rimonabant, explain?
Cardiovascular: Increase heart rate
Other effects: Reddening of the eyes/ dryness of mouth and throat
Self administrated: Influenced by social factors
Subjective effects: Experienced smokers have increased rates of euphoria
Cognitive effects: Slowing of cognitive performance
Appetite: increase food intake
Talking: verbal behavior is decreased
Briefly describe the following effects of marijuana:
Cardiovascular
Other Effects
Self-administration
Subjective Effects
Cognitive Effects
Appetite
Talking
development of new and better drugs for most illnesses. variability of the available medicinal preparations of Cannabis. the active ingredient is insoluble in water and thus not amenable to injectable preparations. taken orally it has an unusually long latency to onset of action.
List the four factors that contributed to the decline prescription rate of the cannabis plant (before 1937).
a glaucoma patient, was arrested for growing marijuana plants on his back porch for medical purposes. began a limited program in which the federal government provided marijuana cigarettes to patients with the FDA’s approval of a ““compassionate use” protocol.
Who was Robert Randall and what role did he play in the history of medical marijuana?
drug used to reduce nausea and vomiting
brand name for dronabinol
generic name for prescription thc in oil in a gelatin capsule
Define the following terms:
Antiemetic
Marinol
Dronabinol
Treating nausea during cancer chemotherapy
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