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Which structure is responsible for forming fingerprints?
dermal ridges
Mammary glands and ceruminous glands are modified versions of:
apocrine glands
Which of the following is true of the stratum basale?
All of the above
Which structure of the hair follicle is a sensory nerve that detects if the hair is touched?
root hair plexus
Which of the following is true of the stratum lucidum?
All of the above
Which layer of the skin is made of dense irregular connective tissue that makes up 80% of the dermal thickness?
reticular layer
Which of the following is true of the stratum corneum?
it is composed of dead cells
Which of the following is true of the stratum spinosum?
the cells are connected together with desmosomes
Which layer of the epidermis has the most mitotically active cells because it is closest to the dermal blood supply?
stratum basale
What is the immediate threat to homeostasis due to burns?
dehydration and electrolyte imbalance
Which type of cell found in the epidermis are star shaped cells that patrol the epidermis and activate the immune system?
dendritic cells
What structures make up the integumentary system?
Hair, skin, nails, sweat glands, sebaceous glands
What are the 6 main functions of the skin?
Protection, Body temperature regulation, cutaneous sensations, metabolic functions, blood reservoir, excretion of wastes
What are the 3 main layers of the skin? How would you describe each layer?
epidermis, dermis, hypodermis
epidermis
(AVASCULAR) superficial region - Consists mostly of keratinized stratified squamous epithelium
dermis
(VASCULAR) underlies epidermis. Mostly consists of fibrous connective tissue
hypodermis (superficial fascia)
Subcutaneous layer deep to the skin. Mostly adipose tissue that absorbs shock and insulates. Anchors skin to underlying structures, mostly muscles
What 4 types of cells can be found in the epidermis?
Keratinocytes, melanocytes, dendritic cells (Langerhans), tactile (merkel) cells
What are the layers of the epidermis and where do you find each (deep to superficial)?
Stratum germinativum (stratum basale)
Stratum spinosum (prickly layer)
Stratum granulosum
Stratum lucidum
Stratum corneum (horny layer)
Describe the stratum basal layer.
Deepest of all epidermal layers, single row of mitotic stems cells, -% melanocytes
Describe the stratum spinosum.
Several layers thick, contains web-like system of intermediate prekeratin filaments attached to desmosomes. Helps to resist tension and pulling, abundant keratinocytes, melanosomes and dendritic cells
Describe the granular layer.
4-6 cells thick (layer is thin since cells are flattened) Keratinization begins
Describe the stratum lucidum (clear layer)
Only find in thick skin (sole of foot or palm). Consists of thin translucent band of two to three rows of clear, flat, dead keratinocytes
Describe the stratum corneum (horny layer)
20-30 rows of flat anucleated keratinized dead cells
Why are cleavage lines important?
Important to surgeons because incisions parallel to cleavage lines heal more readily
What are cleavage lines?
Many collagen fibers running parallel to skin surface
Functions of the hair
warn of insects on skin, hair on head helps guard against physical trauma, protect from heat loss, and shield skin from sunlight
Pili
(hair) flexible strands of keratin
What are fibroblasts function?
They produce collagen fibers to bridge the gap until regeneration is complete
Describe the components of a hair follicle and their functions.
Hair bulb: expanded area at: end of follicle
Hair follicle receptor (or root hair plexus): sensory nerve endings that: wrap around bulb
Hair matrix: actively dividing area of bulb that: produces hair cells
Arrector pili: small band of smooth muscle attached to follicle
Nail matrix
Responsible for nail growth
Eponychium
cuticle
Koilonchya
“spoon nail” abnormal shape of nail, can indicate iron deficiency
Sweat glands (sudoriferous glands)
Eccrine and apocrine sweat glands
Sweat is
99% water (also contains salts, vitamin C, antibodies, dermcidin (microbe-killing peptide), metabolic wastes (lactic acid)
Eccrine gland:
Most common, on palms, soles, and forehead. For thermoregulation
Apocrine glands
Secrete viscous milky or yellowish sweat that contains: fatty substances and proteins
ABCD rule).*
A: asymmetry; the two sides of the pigmented area: do not match
B: border irregularity; exhibits: indentations
C: color; contains: several colors (black, brown, tan, and sometimes red or blue)
D: diameter; larger than: 6mm (the size of a pencil eraser
Describe the 3 steps of tissue repair.
Inflammation sets stage - clotting occurs
Organization restores blood supply - clotting is replace with granulation tissue
Regeneration and fibrosis effect permanent repair scab detaches and fibrous tissue matures