Transduction: The Case of the Piggyback DNA

What serve as genetic vectors in transduction?

bacteriophages (phages)

In _______ _______, random fragments of disintegrating host DNA are taken up by the phage during assembly. Virtually any gene from the bacterium can be transmitted through this mechanism

Generalized Transduction

In _____ ________ a highly specific part of the host genome is REGULARLY incorporated into the virus.

Specialized transduction

The specificity of specialized transduction is explained by the prior existence of a _______ _______ insterted in a fixed site on the bacterial chromosome

temperate prophage

The virulent forms of bacteria such as Corynebacterium diphtheriae, Clostridium spp, and Streptococcus pyogenes all produce _______ with profound physiological effects

Toxins

The _______ forms do not produce _______

nonvirulent (not transduced)

toxins

The toxicity arises from the presence of ________ _____ that have been introduced by transduction

bacteriophage genes

Only those bacteria infected with a ______ _____ are toxin formers

temperate phage