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2 types of refractory periods
Absolute - open Na+ channels, 1-way
Relative - follows after absolute, some K+ open, repolarization happening
What is a good analogy for the Nodes of Ranvier?
“Tab” key analogy
What is different about axon to axon connections?
“all” not “all or nothing”
Cephalization
Formation of central integrator (head). Tied to bilateral symmetry and directional movement
Two theories of neural density trends
Maternal-energy hypothesis
Expensive-tissue hypothesis
What developmental aspect becomes the peripheral nervous system?
The neural crest
What aspect of the head develops faster?
Brain tissue develops faster than the skull, hence the gyri and sulci
What protects the CNS?
Meninges (3 layers)
CSF
BBB
What would you not find in the CSF?
RBC, is it nearly blood plasma
How much weight does the CSF take off the brain?
~98%
Where is CSF produced?
The choroid plexus (ependymal cells)
What do astrocytes do?
Support capillaries and create tight junctions with no pores
Acetylcholine
Excitatory muscles and learning
Dopamine
Reward, attention, motivation
Serotonin
Mood, sexual desire
Glutamate
Excitatory, movement
GABA
Inhibitory
Norepinephrine
fight/flight, emotion, increased HR
Endorphins
Inhibits pains
Octopamine
Invertebrates
NO
Learning and memories
Where did the notochord arise from?
Mesoderm
3 key characteristics of Chordates
Dorsal hollow nerve cord
Pharyngeal pouches
Post-anal tail
The eye contains what percentage of all sensory receptors?
~70%
Transduction
Converting one type of energy into another
The Limbic system contains
Grey matter of the cerebrum, hippocampus, amygdala, mamillary bodies, and hypothalamus
What is the Limbic system responsible for?
“Emotional brain” conscious and subconscious
Cingulate gyrus
Conscious manifestations of emotion
Amygdala
Center for emotional responses
Hippocampus
Short-term memory
Mamillary Bodies
Memory details
Hypothalamus
Pleasure center, stress response
3 PRIMARY Chordate characteristics
Notochord
Dorsal Hollow Nerve Cord
Pharynx
Notochord
Band of specialized cells along the dorsal side of animals, which supports and prevents compression of the body when muscles contract
Dorsal Hollow Nerve Chord
Dorsal tube which integrates the action of the longitudinal muscles of the body wall
Pharynx
Expanded portion of gut with pouches and slits which water passes out of animal (respiration for vertebrates, but filter feeding ancestrally)
Characteristics special to vertebrates
Notochord becomes vertebrae, Dorsal hollow root cord has anterior swelling (brain), sensory organs are concentrated in brain (cephalization), and cranium protects brain
3 layers of the meninges
Outer dura mater, arachnoid membrane, and pia mater
Optic chiasma in sheep
Ventral side, two optic nerves cross over to make an “X”
Lateral ventricle in sheep
Largest cavity
Corpus callosum
Above the lateral ventricle (connects two cerebral hemispheres)
Fornix
White area in between the lateral ventricle and third venticle
Pineal gland
Bulb right in the middle
Pituitary gland
Bulb on bottom
Arbor vitae
White tree lines in Cerebellum
Ampullae of Lorenzini
Shark sensory organs which detect electrical fields
Arachnoid granulations
Whitish bumps that reabsorb the CSF into the venous system
CN I
Olfactory (Smell)
CN II
Optic Nerve (Visual information transfer)
CN III
Oculomotor nerve (opening and moving eye including pupils)
CN IV
Trochlear Nerve (Eye oblique muscle)
CN V
Trigeminal Nerve (Sensation to skin of face and chewing muscles)
CN VI
Abducens Nerve (Movement of lateral rectus muscle of eye)
CN VII
Facial Nerve (facial movements)
CN VIII
Vestibulocochlear nerve (sound from cochlea to brain)
CN IX
Glossopharyngeal nerve (taste)
CN X
Vagus Nerve (organs)
CN XI
Accessory Nerve (Trapezium and sternocleidomastoid muscles)
CN XII
Hypoglossal nerve (Moves tongue)