Molecular biology

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Name the properties of water

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1

Name the properties of water

Cohesive, Adhesive, Thermal, Solvent

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2

Why is water solvent?

Due to polarity, water molecules can separate other polar molecules easily

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3

Why does water have the property of cohesion?

It is due to hydrogen bonds forming between water molecules as a result of polarity (i.e. weak forces of attraction of oxygen and hydrogen atoms)

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4

Why does water have the property of adhesion?

It is due to dipolarity, molecules adhere to polar to hydrophillic surfaces (i.e. atoms in xylem)

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5

What are the thermal properties of water?

High specific heat capacity

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6

Why does water have these thermal properties?

Due to STRONG hydrogen bonds, water has high melting and boiling point

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7

What are the benefits of water having a high specific heat capacity?

It remains a constant temperature, fluctuating very little from the mean. This means, that it makes a good habitat for organisms that reside within the sea, ocean or rivers

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8

What are the benefits of water having a high latent heat of vaporization?

It makes a good coolant, as vaporization allows heat to be taken away from body in sweat

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9

What is an example of cohesion benefiting an organism?

Pulling forces can allow water to be transported to areas of a tree above the ground, through the xylem

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10

What is an example of adhesion benefiting an organism?

Adhesive force between water and cellulose wall allows water to be transported from xylem to cell to keep cell wall moist and primed for gas exchange (also applicable to alveoli)

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11

What is an example of the solvent properties of water benefiting an organism?

It allows for blood withing animals to act as a medium of transportation.

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12

Which substances are carried by their blood, and how?

NaCl, ionic compound so dissolves easily into plasma as ions Na and Cl

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13

Glucose and amino acids are polar so water molecules can easily break weak intramolecular molecular forces them to be dissolved in the plasma

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Oxygen is non-polar, so must be combined with hemoglobin in erythrocytes to be transported

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16

Metabolism

web of all enzyme-catalysed reactions in a cell or organism

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17

Where does metabolism occur?

Cytoplasm, mitochondria, choloplasts

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18

Anabolism

synthesis of polymers from monomers

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19

Catabolism

breaking down of polymers to form monomers

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20

Hydrolysis reaction

E.g. two amino acids form a dipeptide, linked by a peptide bond and one molecule of water

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21

Condensation reaction

E.g. The peptide bond breaks in a dipeptide and an OH and H atoms saturate bonds forming two amino acids

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22

Polypeptide

amino acid

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23

Polysaccharide

monosaccharide (carbohydrate)

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24

lipids

monoglycerides and fatty acids

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25

nucleic acid

nucleotides

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26

Urea

nitrogenous waste produced by break down of polypeptides

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27

What is significant about urea?

It was synthesized in a laboratory falsifying the theory of Vitalism, instead suggesting organic molecules did not have a 'vital force' and instead are not fundamentally different to inorganic molecules

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28

How do the cohesive properties of water explain its surface tension?

The hydrogen bonding between water molecules allows the liquid to resist low levels of external force (surface tension)

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The high surface tension of water makes it sufficiently dense for certain smaller organisms to move along its surface

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31

How do the adhesive properties of water explain capillary action?

Attraction to charged or polar surfaces (e.g. glass) allows water to flow in opposition of gravitational forces (capillary action)

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This capillary action is necessary to allow water to be transported up plant stems via a transpiration stream

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34

Organic compound

a compound that contains carbon and is found in living things

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35

Why is carbon the basis for organic life?

it can form four covalent bonds allowing a diversity of stable compounds to exist

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36

What are the main classes of carbon compounds?

Carbohydrates, lipids, nucleic acids, proteins

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37

What is a carbohydrate composed of?

C,H and O atoms in a common ratio - (CH2O)n

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38

What is a lipid?

Non-polar, hydrophobic molecule comes in variety of forms - simple, complex or derived

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39

What is the function of carbohydrates?

a source of energy (and as a short-term energy storage option) and also as

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a recognition molecule (glycoproteins) and as

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a structural component (part of DNA / RNA)

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44

What is the function of lipids?

component of cell membrane (phospholipid, cholestrol)

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long term energy store (fats, oils)

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signalling molecule

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49

What is a nucleic acid?

DNA and RNA

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50

What is the function of nucleic acids?

To form genetic material, DNA - master code for protein assembly, RNA - manufactures protein

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51

Proteins are composed of which atoms?

C, H, O, N

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52

What is the role of proteins?

Major regulatory molecules involved in catalysis (enzymes)

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structural molecules

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role in cellular signalling

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57

Describe the structure of an amino acid

Amine: NH2

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Carboxyl: COOH

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Variable R group

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Hydrogen atom: H

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64

Describe the structure of a nucleotide

Phosphate group: 3(O)-P=O

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Pentose sugar

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Nitrogenous base

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69

How are glycerol and fatty acids joined to make triglycerides?

ester linkages

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70

How are monosaccharides joined to form polysaccharides?

glycosidic linkages

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71

How are amino acids joined to form polypeptide chains?

peptide bonds

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72

How are nucleotides joined to form polynucleotide chains?

phosphodiester bonds

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73

What are the polymers of glucose?

glycogen, cellulose and starch

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74

Name two reasons for metabolism

They provide a source of energy for cellular processes (growth, reproduction, etc.)

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They enable the synthesis and assimilation of new materials for use within the cell

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77

Name three examples of monosaccharides

glucose, galactose, fructose

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78

Name three examples of disaccharides

lactose, maltose and sucrose

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79

Name three examples of polysaccharides

cellulose, glycogen and starch

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80

What is the function of monosaccharides?

immediate energy source

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81

What is the function of disaccharides?

transport

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82

What is the function of polysaccharides?

long-term energy store, cell structure or cell recognition

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83

What is the structure of cellulose?

linear molecule composed of ฮฒ-glucose subunits (bound in a 1-4 arrangement)

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84

What is the function of cellulose?

structural polysaccharide found in cell wall of plants, cannot easily be digested by most animals due to lacking specific enzyme

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85

What is the structure of starch?

energy storage composed of ฮฑ-glucose subunits (bound in a 1-4 arrangement) exists in one of two forms - amylose or amylopectin

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86

Distinguish between amylose and amylopectin in terms of structure and function.

Amylose - linear (helical) molecule: harder to digest and less soluble but takes up less space (preferred storage form in plants)

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Amylopectin - branched (contains additional 1-6 linkages)

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89

What is the structure of glycogen?

energy store composed of ฮฑ-glucose subunits linked together by both 1-4 linkages and 1-6 linkages (branching)

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It is similar to amylopectin, but more highly branched (every 20 compared to 10)

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92

Fatty acids that possess no double bonds are...

saturated

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93

Fatty acids with double bonds are...

unsaturated

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94

Structure of unsaturated fatty acids

Bent (double bond)

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95

Structure of saturated fatty acids

Linear

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96

Types of fatty acid

saturated, monounsaturated (one double bond), polyunsaturated (several double bonds)

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97

Distinguish between cis and trans unsaturated isomers

Cis: The hydrogen atoms attached to the carbon double bond are on the same side

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Trans: The hydrogen atoms attached to the carbon double bond are on different sides

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100

Which isomer of unsaturated fatty acid is not naturally occurring?

Trans, produced by industrial process of hydrogenation to maintain linear structure and thus remains solid at room temperature

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