Rheumatology drugs

What are side effects of antigout medications? ________, __________, _________

-GI upset

-Myopathy

-Stevens-Johnson Syndrome, DRESS syndrome

What are the interactions with antigout medications? ________, ________

-Statins raise myopathy risk

-Antigout increases warfarin efficacy

What is the indication for Disease-Modifying Antirheumatic Drugs (DMARDs)?

Autoimmune disorders

Side effects of DMARDs?

-Cancer risk

-Immune suppression

Interactions with DMARDs?

-Other immune suppressants

-Live vaccines (infection risk)

What is the indication for bisphosphonates?

Osteoporosis

Side effects of bisphosphonates? ________, __________

-Esophageal irritation

-ONJ (osteonecrosis of the jaw)

Interaction to keep in mind for bisphosphonates?

-Dental trauma raises risk of ONJ

Colchicine

Colcrys

Anti-gout

Allopurinol

Zyloprim

Antigout. Can cause massive gout flare upon start

Hydroxychloroquine

Plaquenil

DMARD

Methotrexate

Trexall

DMARD

Adalimumab

Humira

DMARD

Etanercept

Enbrel

DMARD

Upadacitinib

Rinvoq

DMARD

Alendronate

Fosamax

Bisphosphonate (osteoporosis)

Ibandronate

Boniva

Bisphosphonate (osteoporosis)

Risedronate

Actonel

Bisphosphonate (osteoporosis)

Zoledronic acid

Reclast

Bisphosphonate (osteoporosis)

IV once a year

Teriparatide

Forteo

osteoporosis treatment

Denosumab

Prolia

Osteoporosis treatment

Raloxifene

Evista

osteoporosis treatment