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what is nutrition?
The interrelated steps by which a living organism assimilates food and uses it for growth, tissue repair and replacement, or elaboration of products
what is a nutrient?
A substance that provides the nourishment essential for growth and the maintenance of life
what are the 6 main nutrients?
carbohydrates, proteins, fats, vitamins, minerals, water
difference between minerals and vitamins
vitamins = organic compounds, specific role in metabolism
minerals = inorganic components of plant and animal tissues
What is the primary function of enzymes?
To act as catalysts in metabolic reactions.
What do enzymes do to chemical reactions?
They accelerate chemical reactions.
What happens to enzymes after a reaction?
They return to their normal form post reaction.
Are enzymes substrate specific?
Yes, enzymes are substrate specific.
What do enzymes work with to shuttle substrates?
Cofactors and coenzymes.
What are hormones?
Substances that are produced in one tissue and transported to a target tissue.
How is the production and release of hormones regulated?
By positive or negative feedback.
digestion
The preparation of food for absorption, either mechanical, chemical, enzymatic
absorption
The process by which nutrient molecules pass through the wall of the digestive system into the blood or lymph systems
metabolism
The summation of biochemical processes in living tissue
catabolism
breakdown or oxidation of fuels
anabolism
synthetic reactions that build up tissues
carnivores
short uncomplicated large intestine, highly digestible diet
herbivores/omnivores
More complicated Gastrointestinal tracts (GI), Diet varies in digestibility, Modified to improve utilization of plant tissue
monogastrics
single compartment stomach, auto enzymatic, one long tube
ruminants
4 compartment stomach, alloenzymatic, regurgitate feed to chew a second time
hindgut fermentors
one compartment stomach, enlarged cecum, both mono gastric and ruminant digestion
cecal fermentors
capybara, rabbit, rat
primary site of fermentation is the cecum
colonic fermentors
horses, donkeys, humans
primary site of fermentation is the colon
salivary ducts
added during mastication, used to moisten the mouth
amylase
begins to digest starch
bicarbonate and mucin
neutralize stomach acid
why does salivary ducts have a greater importance in ruminants?
dds base to maintain proper pH (very acidic stomach), also allows for bolus to be created
What type of saliva is thin and watery?
Serus saliva
Which salivary glands produce serus saliva?
All three salivary glands
What type of saliva is very viscous (thick)?
Mucus saliva
Which salivary glands produce mucus saliva?
Submaxillary and sublingual glands
submaxillary salivary glands
base of tongue (mandibular)
sublingual salivary glands
underneath the tongue
parotids salivary glands
below the ear
esophagus
A muscular tube that connects the mouth to the stomach.
What is the primary site of chemical digestion?
Stomach
What type of tissues line the stomach to prevent stomach acid from damaging the stomach wall?
Mucosal tissues
How many separate areas is the stomach divided into based on the glands present?
Four
What are the names of the four areas of the stomach based on the glands present?
Esophageal, cardiac, pyloric, fundic
esophageal region
extension of the esophagus, most common area for ulcers
cardiac region
produces primarily mucus, protects stomach from gastric secretions, largest region in swine
which areas in the stomach area are primarily used for storage?
cardiac and esophageal region
What is the lining of the peptic/fundus region covered with?
Gastric pits
What do gastric pits open into?
Gastric glands
What do gastric glands produce?
A mixed secretion of acid, enzymes, and mucus
What are the two main types of cells in gastric glands?
Chief/peptic cells and parietal/oxynitic cells
chief/peptic cells
produces proteolytic enzymes
parietal/oxynitic cells
produce HCl
pyloric region
mucus producing cells
small intestine
highly coiled, most absorption occurs here, large surface area -> folds/villi, divided into 3 sections
duodenum
1st part of small intestine, produces various digestive secretions, pancreatic and bile secretions enter as well, lowest pH
jejunum
site of absorption, longest portion of SI, forms many coils
illeium
site of absorption, short and straight
What are villi in the small intestine?
Small fingerlike projections.
What do villi in the small intestine contain?
An arteriole, a venule, and a lacteal.
What is a lacteal?
A drainage tube to the lymphatic system.
Where do villi develop in the small intestine?
In the crypts of Lieberkühn.
SI brush border
microvilli and glycocalyx, help to catch particles for digestion
large intestine
made up of the cecum, colon, rectum, generally larger in herbaceous species, primary role is water and electrolyte absorption, some microbial fermentation occurs
liver
compact undivided gland, produces BILE, active site of synthesis and detoxification of metabolites
pancreas
light colored lobulated gland, produces pancreatic juice which contain enzymes to help with digestion -> amylolytic, lipolytic, proteolytic
where are digestive enzymes found?
saliva - small amount, glandular stomach - major source of proteolytic and HCl (produced in peptic gland region)
pancreas - important source of proteolytic, amylolytic, and lipolytic
small intestine - glandular wall of duodenum produces sugars, proteolytic, and lipolytic
Amyloytic enzymes prefer what substrates?
carbohydrates
proteolytic enzymes prefer what substrates?
protein
lipolytic enzymes prefer what substrates?
lipids
bilirubin
orange-yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells are destroyed
pepsin
proteolitic, secreted as proenzyme pepsinogen
rennin (chymosin)
secreted only in young animals, develops a milk clot, prevents overload of intestines
fat digestion
Result of emulsification of bile salts and the enzymatic action of pancreatic and intestinal lipases
Pancreatic lipase hydrolyzes fatty acids to produce 2 free fatty acids and 2 monoglycerides
Bile salts and hydrolyzed fats form the micelles which increase the surface area of the fat droplet
is the GI tract different in avians than other animals? true or false
true
what happens in the proventriculus?
gastric juices are produced
what does the gizzard (ventriculus) do?
used to mechanically reduce particle size
Do ruminants have upper incisors?
no
what are the 4 compartments of the ruminant stomach?
rumen, reticulum, omasum, abomasum
What does the reticulum move food into?
The reticulum moves food into the rumen and omasum.
What process does the reticulum facilitate?
The reticulum facilitates the regurgitation of ingesta.
Is there a true wall separating the rumen and reticulum?
no
rumen
large fermentation vat where bacteria and protozoa work, wall covered in papilla (increases surface area), serves as a point of microbial digestion
omasum
nickname is "many piles", role is not completely understood, aids in particle size reduction, helps control passage rate of ingesta, some absorption occurs
abomasum
similar to the glandular stomach in non-ruminants, provides chemical digestion of feed, different from other animals since feed has already gone through microbial digestion
pre-ruminants
young animals have an underdeveloped rumen, reticulum, and omasum
after consuming solid food stomach will reach adult proportions
reticular groove
Present in young ruminants so the milk they drink can bypass the rumen/reticulum into the abomasum
What is the process that occurs in the rumen before gastric digestion?
Microbial digestion
What type of environment do the reticulum and rumen provide for microbes?
Warm and moist
what 3 types of microorganisms are in the rumen?
bacteria, protozoa, and fungi
what two groups are carbohydrates divided into for ruminants?
fibrous (cellulose, hemicellulose) and readily available (sugars, starches)
what are readily available carbs digested by the microbes converted to?
VFA (acetate, propionate, butyrate)
what happens if an unadapted ruminant is fed readily available carbs?
increased risk of acidosis
what microorganisms consume dietary protein and resynthesize it?
proteolytic
what can ruminants use to meet protein needs?
non-protein nitrogen
anaerobic fermentation percentages in ruminants
CO2 - 65%
CH4 - 25%-27%
N - 7%
rumination
partially digested feeds regurgitated, allows for more complete chewing, increases saliva incorporation, spend about 8 hours/day doing this
what causes longer rumination?
course diets
eructation
The expulsion of gases orally; burping or belching.
what happens if the esophagus is blocked and a ruminant has a lot of gas?
bloat
what does the cranial parasympathetic neurons via the vagus nerve control?
esophagus, stomach, small intestine, and proximal portions of the large intestine
sacral segment of the spinal column controls?
distal portion of the colon, rectum, internal anal sphincter
nutrients pass across _______ in blood and lymph
the epithelial cells and into blood or lymph capillaries
nutrients are carried by ________ in blood and lymph
by portal vein to the liver or thoracic duct to the heart
where does the blood and lymph move waste to?
kidneys, where it can be filtered and excreted
waste can also move to intestinal epithelium to be excreted