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Define Ebola
An infectious and frequently fatal disease marked by fever and sever internal bleeding, spread through contact with infected body fluids by a filovirus (Ebola virus).
Other known name for Ebola
Ebola haemorrhagic fever
Incubation Period
time of infection with the virus to onset symptoms, is from 2-21 days
How long can a corpse be contagious for?
Up to 7 days
Can you Spread the disease without having developed symptoms?
No
Identify the symptoms
Day 7-9: headache, fatigue, fever, muscle soreness
Day 10: sudden high fever, vomiting blood, passive behavior
Day 11: Bruising, brain damage, bleeding from nose, mouth, eyes and anus.
Day 12: Loss of consciousness, seizures, massive internal bleeding, death.
Treatment
Vaccine
Ervebo vaccine approved in December 2020 for individuals 18 years or over for protection against Zaire Ebola Virus.
Vaccine administered to more than 350 000 people in guinea and in the 2018-2020 outbreaks in the DRC.
May 2020 two component vaccine was authorized to individuals 1 year and older. however not suitable for immediate outbreak response as it is taken in two separate doses.
Morbidity
The condition of being diseased
Mortality
The state of being subject to death, especially a large scale
When did Ebola first appear?
1976
Types of Ebola and Average death rate of each
Zaire Ebola virus 68%
Sudan Ebola virus 53%
Bundibugyo Ebola virus 27%
Reston Ebola virus 0%
Tai Forest Ebola virus 0%
How Ebola affects the body
Transmission
Natural Host: Fruit bats
Source of Human Infection: Blood, secretions, organs or other bodily fluids of infected animals, bushmeat.
Epizootic Cycle
Ebola produces high mortality among other primates and animals.
Humans interaction with Ebola animal hunting.
Human to Human spread.
Zaire Ebola case fatality rate
68%
Spatial Distribution of Ebola
Has been isolated to the continent of Africa.
Democratic republic of congo
sudan
uganda
republic of congo
guinea
liberia
siera leone
nigeria
Post 2014-2016 outbreak Ebola has been recorder in
Sengal, USA, Spain, Italy
Due to exposed healthcare workers.
Outbreaks of Ebola have been found in monkeys and pigs in the Phillipines and China.
Temporal Distribution
Epidemic
When 3 or less countries are affected by a disease.
Pandemic
More than 3 countries are affected by the disease.
physical processes influencing distribution:
Climate - foraging behavior of species is strongly influenced by seasonally driven temporal and spatial clustering of scarce fruit resources which increases Ebola locations. Outbreaks are most likely to occur in times of high humidity due to the increased fruit production in the eating habitats of animals that can lead to transmit Ebola, making the virus become more active. Areas of higher rainfall: roads become impassable which is difficult to seek healthcare and implement infection contact measures which directly increase the risk of Ebola transmissions
Geographical location - most outbreaks contained to remote rural areas and were controlled rapidly with the help of the WHO and international partners. each outbreak has lasted for periods averaging 3 weeks to 3 months. West African outbreak different in that cases reached capital cities with higher levels of population density and the virus was able to spread quickly, fruit bat is the host for both human and animal disease making the spatial distribution of Ebola influenced by the natural territory of the bat.
Human processes influencing distribution:
Caring for the sick - Ebola is transmitted through biological fluids rapidly increasing the rate of infection within communities. e.g caring for sick relatives or community members, assisting with their cleaning and feeding during a period of illness.
Fleeing and seeking refuge - during height of Ebola epidemic the natural human response was to flee the outbreak with relatives and friends across borders where those spread the disease into neighboring countries and cities.
Economy - Ebola can be magnified due to the establishments of road networks, agricultural practices and population migration to urban areas. Changing dynamics resulted in rapid and widespread transmission of the virus from a single case in rural guinea to a total of 28 616 cases in 5 African nations and 4 international communities in 2014-16.
Health System - (in West Africa) weak healthcare system, poorly prepared, people did not believe Ebola was real, no familiarity for clinical diagnosis, laboratory support for clinical diagnosis was not established, facilities not adequately resourced.
Magnitude
high case of fatality rate of about 6.6%
3481 cases 2299 deaths and 1162 survivors
2018-2020 DRC outbreak second largest Ebola outbreak globally
Duration
began August 2018 ended 25th June 2020 lasting about 23 months
Frequency
high frequency and recurrent
DRC experienced 12 Ebola outbreaks since the virus was first identified in 1976
Probability
moderate to high in some regions
risk is higher in forested areas and areas with conflict, population movement, weak health systems and delayed treatmetn increase transmission