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Mortality
# of deaths caused by disease
Pulled from death certificates
Morbidity
Absense of health/presence of illness
Prevalence
# of people who have a disease
Pulled from hospital admission records
Incidence
# of new cases of a disease
CVD
#1 killer in all population groups
Highest CVD death rates
Black + Latino/Hispanics
Right atrium
Receives blood with low oxygen content
Right ventricle
Low-oxygenated blood goes from here to lungs
Lungs
Add oxygen to blood
Left atrium
Oxygenated blood goes from lungs to here
Left ventricle
Oxygenated blood goes from here to tissue/muscles
Arteries
Carry oxygen-rich blood away from the heart
Veins
Carry oxygen-low blood back to the heart
Coronary arteries
Arteries that specifically supply the heart muscle itself with oxygen-rich blood
The chambers of the heart don’t feed the heart muscle directly
Atherosclerosis
Narrow/blocked arteries
Plaque build-up of fats, cholestrol, etc
If blood cannot reach parts of the heart, that section is starved of oxygen → MI
CO/Q
Cardiac Output
SV x HR
Left ventricle
PVR: Peripheral Vascular Resistance
Prevention of blood flow
Cardiorespiratory system purpose
Deliver oxygen
Remove waste
Transport nutrients
Regulate temperature
Purposes of CR system dependent on CV
Waste removal, nutrient transportation, temperature regulation transportation
Central Oxygen Transport System
Heart: delivery and transportation of oxygen
CO = HR x SV
Oxygen: lungs → blood → muscles
Peripheral
Muscles + tissue: utilization of oxygen
Extract and use the oxygen from the blood
a-vo2 difference
Arteries
Takes deoxygenated blood AWAY from the heart
a-VO2 difference
O2 in arteries - O2 in veins
High a-VO2 difference
A lot of oxygen used
Factors that influence response to acute changes
Fitness status
Temp/humidity, time of day, amt of sleep
Amt of food/caffeine
Alc/tobacco
Anxiety
Anticipatory phase
Recognizing that it’s time to work out
Parasympathetic withdrawal
Sympathetic drive
Parasympathetic system
Brings down heart rate
Sympathetic system
Brings up heart rate
Norepinephrine, epinephrine
Fight-or-flight
Heightened senses
Steady state
The leveling-off of your heart rate at the max HR after about 1-3 mins
Harder workload
Takes longer to reach steady state
More trained individuals
Reach steady state faster
Factors affecting stroke volume
Venous return to heart
LV capacity to enlarge
Contractility force of heart
Arterial pressure
Sympathetic stimulation
Venous return to heart
Getting the blood to the heart → gets stronger/bigger
LV capacity to enlarge
Contain the blood and handle it
Contractility force of heart
Can the heart send out the blood?
Will increase force once stronger/bigger
Arterial pressure
Blood leaving the heart (arteries → away)
Higher pressure means lower SV
Vasodilation
Vasodialation
Increasing the diameter of the arteries to let more blood flow through
McArdle, Katch, and Katch
Compared CO during exercise upright vs. supine
Cardiac output higher on SUPINE activity
Supine CO higher because of …
SV
Reduced gravity when lying down → easier venous return → more blood in heart → greater SV
Blood doesn’t have to travel vertically up to the heart
Strictly increase with exercise intensity
Systolic BP
HR
Stay the same as exercise intensity increases
Mean arterial pressure
Increases until 40-60% VO2 max as exercise intensity increases
Stroke volume
Increases then slope decreases with exercise intensity
Cardiac output
a-VO2 difference
Both HR and SV influence CO
Before 40% VO2 max
Cardiovascular changes with acute exercises
Size
Age
Genetics
Sex
Level of fitness
Increases linearly with exercise intensity
VO2
Static exercise
Big ↑ in BP, smaller ↑ in HR
Compression of blood vessels, ↑ TPR
Dynamic exercise
Moderate ↑ BP, ↑ HR
Rhythmic contraction, good blood flow
Valsalva maneuver
Breath-holding causes increased BP
Compressed vessels
O₂ deficit
When you start working out: the difference between the amount of oxygen you have readily available vs. the amount you need
O₂ debt
When you finish working out: the difference between the amount of oxygen your exercised-body is producing vs. how much oxygen you actually need
Cool down stage → need less oxygen than when you were exercising