Microbiology Fungi & Protozoan Cardiovascular & Lymphatic Diseases

Cardiovascular & Lymphatic Diseases (4)

- visceral leishmaniasis

- malaria

- chagas' disease (american trypanosomiasis)

- toxoplasmosis

visceral leishmaniasis protozoan infection

Leishmania donovani

visceral leishmaniasis transmission

sand fly bites (typically in tropics)

visceral leishmaniasis abilities (3)

- spreads protzoan & enters bloodstream

- survive inside macrophages & multiply

- opportunistic with HIV

Malaria protozoan

Plasmodium (plasmodium falciparum)

malaria transmission (2)

- mosquito bites

- endemic in tropical areas

malaria matures in stages to infect a...

red blood cell (RBC)

malaria stages (3)

- sporozoite

- merozoite

- trophozoite

malaria sporozoite stage (2)

- carried by female mosquito

- enters bloodstream & changes in liver

malaria merozoite stage

- liver cells rupture & merozoites invade RBC to multiply

malaria trophozoite stage

RBC ruptures periodically to release new merozoites -> rise in body temp

when is malaria most symptomatic

when cell ruptures

malaria control

pesticide to control mosquito population

why can't malaria have a vaccine

problem finding the stage of the organism that provides protection against the infection

Chagas' disease (american trypanosomiasis) protozoan

trypanosoma cruzi

Chagas' disease (american trypanosomiasis) transmission

reduviid bug

Chagas' disease (american trypanosomiasis) abilities

- can cross placenta

- can be chronic (multiply in host cells)

Toxoplasmosis protozoan

toxoplasma gondii

Toxoplasmosis transmission (2)

- feces of cats as oocytes

- consumption of undercooked contaminated meat

Toxoplasmosis abilities (4)

- mature to trophozoite in host cells

- self-limiting (cures itself)

- can cross placenta

- opportunistic infection