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Atmospheric pressure (Patm)
Amount of force that is exerted by gases in the air surrounding any given surface
Intrapulmonary pressure (Palv)
Pressure of air within the respiratory system that is measured at the alveoli
Intrapleural pressure (Pip)
Pressure in the pleural cavity
Mesothelial cell
Cells that monitor the level of pleural fluid in the pleural cavity
Transpulmonary pressure
Difference between the intrapleural and intrapulmonary pressures at a given time
Boyle’s law
The pressure of a gas is inversely proportional to its volume at a constant temperature; P = k/V
Surface tension
Cohesive force at the surface of a liquid that makes it contract and resist being stretched or broken; important in liquid film lining alveoli
Thoracic wall compliance
Ability of the thoracic wall to stretch while under pressure
Pulmonary fibrosis
A condition where lung tissue becomes thick, stiff, and scarred, resulting in decreased lung compliance
Quiet breathing/eupnea
Mode of breathing that occurs at rest and does not require conscious control; inhalation is active and exhalation is passive
Diaphragmatic breathing
Type of breathing where the diaphragm contracts and flattens to increase lung volume
Costal breathing
Type of breathing where the external intercostal muscles contract and elevate the ribs, slightly increasing the thoracic volume
Forced breathing/hyperpnea
Mode of breathing where there is an active manipulation of breathing; both inhalation and exhalation are active and require the use of accessory muscles in addition to primary ones
Cough
Taking a deep breath, closing the glottis, and then forcing air superiorly from the lungs against the glottis, causing it to open suddenly and release a burst of air through the oral cavity; used to clear lower respiratory passageways
Sneeze
Expelling a burst of air through the nasal cavity while the uvula depresses and closes off the oral cavity; used to clear upper respiratory passageways
Hiccups
Sudden inspirations resulting from the spasm of the diaphragm; sound occurs as air hits the vocal folds
Yawn
Very deep inspiration that ventilates all alveoli, opening any that may have become closed during regular respiration
Pneumothorax
Condition where air enters the pleural cavity, breaking the fluid bond that pulls the lungs outward towards the chest; often the cause of lung collapse
Atelectasis
Partial lung collapse
Dalton’s law
The total pressure of a mixture of gases is equal to the sum of the partial pressures of each gas that is present; Ptotal = P1 + P2 + P3 + …
Residual volume
Amount of air that can never be exhaled
Charles’ law
At a constant pressure, the volume of a gas is directly proportional to its temperature; V1/T1 = V2/T2
Henry’s law
The concentration of gas dissolved in a liquid is directly proportional to the solubility and partial pressure of that gas
Nitrogen narcosis
High amounts of nitrogen dissolving in deep waters due to an increased partial pressure of nitrogen
Ventilation
Movement of air into and out of lungs
Perfusion
Flow of blood in the pulmonary capillaries
Ventilation-perfusion coupling
The matching of airflow and blood flow in the lungs to ensure efficient gas exchange