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Fundamentals of biology
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Euchromatin
Loosely coiled, active chromatin that can be transcribed by RNA polymerase and transcription factors.
Heterochromatin
Tightly coiled, inactive chromatin where genes are hardly ever transcribed.
Interphase
The phase of the cell cycle divided into three stages: G1 (Gap), S (Synthesis), and G2 (Gap 2).
G1 Phase
First gap phase where the cell performs its everyday functions.
S Phase
Synthesis phase of interphase where DNA is replicated.
G2 Phase
Second gap phase where the cell prepares for division by growing and producing organelles.
Cell Cycle
The life cycle of a cell consisting of G1, S, G2, and M phases.
Meiosis
Special cell division in sexually reproducing organisms that reduces diploid (2n) cells to haploid (n) gametes.
Meiosis I
The first division of meiosis where homologous chromosomes separate.
Meiosis II
The second division of meiosis where sister chromatids separate.
Crossing Over
The exchange of genetic material between homologous chromosomes during prophase I of meiosis.
Euploidy
The correct number of chromosomes in a species for multiples of that set.
Aneuploidy
A change in the chromosome number resulting from nondisjunction.
Nondisjunction
The failure of homologous chromosomes or sister chromatids to separate normally during cell division.
Monosomy
A condition where a zygote has only one copy of a particular chromosome.
Trisomy
A condition where a zygote has three copies of a particular chromosome.
Turner Syndrome (X0)
A condition in females characterized by the presence of a single X chromosome.
Klinefelter Syndrome (XXY)
A condition in males involving an extra X chromosome, leading to underdeveloped testes.
Spermatogenesis
The production of sperm cells through meiosis.
Oogenesis
The production of egg cells, where one of the four nuclei becomes the egg and the others become polar bodies.
Genetic Variation
Differences in DNA that can occur as a result of mutations and recombination during meiosis.
Gametes
Haploid cells produced through meiosis that fuse during fertilization to form a diploid zygote.
Zygote
A diploid cell formed from the fusion of two haploid gametes.