Skeletal Muscle Contraction
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10 Terms
starts with neuron releasing ACh
What is step 1 of skeletal muscle contraction?
ACh binds to receptors, ligand channel opens
What is step 2 of skeletal muscle contraction?
Sodium flows in, depolarizing the cell
What is step 3 of skeletal muscle contraction?
Action potential, opens voltage-gated sodium channels, more sodium comes in
What is step 4 of skeletal muscle contraction?
Signal spreads across the membrane and down the T-tubules
What is step 5 of skeletal muscle contraction?
causes release of calcium from the sarcoplasmic reticulum
What is step 6 of skeletal muscle contraction?
calcium binds to troponin, moves tropomyosin
What is step 7 of skeletal muscle contraction?
myosin hydrolyzes ATP and binds to actin which from a cross-bridge
What is step 8 of skeletal muscle contraction?
myosin head tilts forward (power stroke), and causes the filaments to slide past each other
What is step 9 of skeletal muscle contraction?
myosin remains attached to actin until ATP binds to it, which breaks the bond and cross-bridge. Then myosin returns to resting state
What is step 10 of skeletal muscle contraction?