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What are cells made of?
Macromolecules
What drives what the cell can do?
Macromolecules
What are the four basic combinations of atoms?
Macromolecules
What are the small organic building blocks of the cell?
Sugars, fatty acids, amino acids, nucleotides
What are the four macromolecules?
Carbohydrates, lipids, proteins, nucleic acids
What are the structures of nucleotides?
Nitrogenous base, sugar, and phosphate group
Does DNA or RNA use thymine?
DNA
Does DNA or RNA use uracil?
RNA
Does adenine or guanine have three bonds?
Guanine
What is the basic structure of amino acids?
Amino group, carbon, carboxyl group
Why do proteins have so many different functions?
They have so many different structures
What do you look for to recognize a peptide bond?
C = O
What are the levels of folding to create functional proteins?
Disulfide bonds, hydrogen bonds, ionic bonds, and Van der Waals and hydrophobic interactions
What are lipids made up of?
Hydrophilic head and couple of hydrophobic fatty acid tails
What is the hydrophilic head of a lipid made up of?
Polar group, phosphate, glycerol
What causes variability in the lipid/phospholipid billayer?
Variability in the polar head group
What is energy?
The capacity to cause specific physical or chemical changes
Where do phototrophs get their energy from?
Light
What are the different kinds of biological work?
Synthetic, mechanical, concentration, electrical, heat production, bioluminescence
What is an example of synthetic work?
Photosynthesis
What is an example of mechanical work?
The contraction of a weight lifter’s muscles
What is an example of concentration work?
The accumulation of molecules in a cell
What is an example of electrical work?
The membrane potential of a plant cell
What is an example of heat production?
Shivering in the cold
What is an example of bioluminescence?
The courtship of fireflies
What is synthetic work?
Work of making something
What is mechanical work?
Physical movement of something
What is concentration work?
Accumulation of things
What is electrical work?
Focus on charge aspect of an ion
What is lost in the flow of energy?
Heat losses
How does energy flow?
One way; it doesn’t cycle
What membranes will be relatively stiff?
Contain mostly phospolipids with no double bonds
What does the amphipathic nature of fatty acid-containing phospholipids do?
Drives the formation of a bilayer which serves to isolate water and hydrophilic molecules on either side
What are the functions of carbohydrates?
Energy storage, structural stability, binding sites for proteins
What does a positive change in entropy favor?
The progress of a reaction from reactants to products
What process involves an increase in entropy of the system?
Combustion of paper
What is the storage of glucose molecules by linking them together in the form of glycogen an example of?
Synthetic work
What is entropy?
The measure of disorder or inability to do work in a system
What is enthalpy?
The measure of total heat content in a system
What is activation energy?
The minimum amount of energy reactants must contain before collisions between them will be successful in giving rise to products
What does a catalyst do?
Lowers energy required for activation
What is the active site?
The location on an ezyme where substrates bind and the catalysis occurs
What is a reversible inhibitor?
Inhibitors that binds in a noncovalent matter, has free and bound forms
What is an irreversible inhibitor?
Inhibitor that binds covalently to the enzyme and is usually toxic to cell
What is substrate-level regulation?
Controlling the concentration of substrate available to the enzyme
What is allosteric regulation?
Molecule other than substrate or immediate product regulates the enzyme
What is covalent modification?
Addition or removal of a functional group/amino acid sequence to an enzyme that affects its conformation and ability to bind substrate
What does covalent modification of phosphate groups do?
Regulates enzyme activity
What do kinases do?
Add phosphate groups
What do phosphotases do?
Dephosphorolate