Microbiology Fundamentals: Viruses and Prions

Flashcards covering classification, structure, replication, and pathogenicity of viruses and prions.

What are the main criteria for virus classification according to the newer systems?

Hosts and diseases they cause, structure, chemical composition, similarities in genetic makeup.

Who is responsible for classifying and categorizing viruses?

The International Committee on the Taxonomy of Viruses.

What is a capsid?

A protein-rich shell constructed from subunits called capsomeres.

What term is used for viruses that consist of only a nucleocapsid?

Naked viruses.

What is the role of spikes on viruses?

To serve as a key to let them into host cells.

What are the general phases of the animal viral replication cycle?

Adsorption, penetration and uncoating, synthesis, assembly, release.

What happens if a cell lacks compatible virus receptors?

The virus cannot obtain access to the cell.

What is a provirus?

Viral DNA that incorporates into the DNA of the host.

What is lysogenic conversion?

Phage genes in bacterial chromosomes cause the production of toxins or enzymes that enhance pathogenicity in humans.

What type of viruses may lead to cancer?

Oncoviruses.

What diseases are caused by transmissible spongiform encephalopathies (TSEs)?

Examples include Kuru, Scrapie, and Classic CJD.