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what do you think would happen if the corpus luteum dissolves?
Progesterone levels drop
How long is a normal menstrual cycle?
21-35 days (ACOG) or 24-38 days (FIGO)
What is cycle variation?
The difference between the longest and shortest recorded menstrual cycle
Severe discomfort and cramping during a period is known as what?
dysmenorrhea
endometrial growth in the uterine muscle wall
Adenomyosis
endometrial growth outside of the uterus
Endometriosis
Reproductive cancer are what
cancers that start in the sex organs
What are some of the reasons motivating the change in name from PCOS to PMOS?
diagnosis delays, stigma, research, consensus/transition
What is a Delphi survey
Structured questionnaire for experts (goal: reach a consensus on a topic)
The “Implications” section details genetic, organ system, biochemical pathway disruptions driving the symptoms of PMOS. Two hormones that we discussed last week are mentioned (GnRH and LH). Briefly describe how they relate to PMOS symptom onset
Disruption in GnRH pulsing causes an increase in LH which drives excess ovarian androgens, contributing to hyperandrogenism
Briefly, describe the concerns with including the term “ovarian” or other ovary-related words in the new name. Why was it preferred over the term “reproductive”
Some respondents were worried that it would be an incomplete representation of multi- system effects and imply irrelevance after menopause. However, it was preferred over reproductive because respondents felt that it reduced stigma in certain regions. Furthermore, “ovarian” encompasses endocrine, follicular, and ovulatory disturbances whereas “ovary” and “ovulatory” does not