Cephalosporins - Generic -> Generation, Use, Special Considerations

Worry About Dosing Later - Brand Name use the other set

Cefazolin

• First Gen

• Surgical PPX

Cephalexin

• First Gen

• Skin Infection, MSSA

Cefuroxime

• Second Gen

• Acute Otitis Media, CAP

Cefotan

• Second Gen

• Anaerobes (B Fragilis), GI Surgical PPX

• DO NOT TAKE WITH ALCOHOL - disulfram-like rxn

Cefoxitin

• Second Gen

• Anaerobes (B Fragilis), GI Surgical PPX

Cefdinir

• Third Gen

• Acute Otitis Media

Ceftriaxone

• Third Gen

• CAP, meningitis, spontaneous bacterial peritonitis, pyelonephritis

• No renal dosing

• DNU in neonates (0-28 days) - Kerniterus

Cefotaxime

• Third Gen

• CAP, meningitis, spontaneous bacterial peritonitis, pyelonephritis

Ceftazidime

• Third Gen

• Pseudomonas

Cefepime

• Fourth Gen

• Pseudomonas

Ceftaroline

• Fifth Gen

• MRSA, CAP, SSTI