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Mood Disorder
change in mood that is persistent for longer than 2 weeks; is often accompanied by physical, emotional, and functional deficits; can be related to other factors like stressors, illness, or substance abuse
Anhendonia
lack of pleasure in previously pleasurable activities
To be diagnosed with major depressive episode:
***must have 5 or more of the below to meet criteria + depressed mood/anhendonia
-appetite disturbance/weight change
-sleep disturbance (most common symptom)
-psychomotor agitation
-loss of energy/fatigue
-feelings of worthlessness
-decreased concentration/cognition
-recurrent thoughts of death/suicide
-self-rejection
To be diagnosed with depression PT 2:
-symptoms must last for at least two weeks
-symptoms causes significant social, occupational, or interpersonal functioning
Persistent Depressive Disorder
-also known as Dysthymia; chronic depression w/o complete remission for two years or more
***episodes of major depression with incomplete remission b/t episodes
Adjustment Disorder
-mood change in reaction to identifiable stressor
-symptoms are brief in duration
-generally do not require pharmacology to treat
Manic Episode
-elated, euphoric, "giddy" mood
-inflated sense of self-esteem
-thought processes are racing yet goal-oriented
-can be focused on topics such as religion, sexuality, business, etc.
-speech pressured, difficult to interpret
-lacks need for sleep
-excessive foal-directed activity with high risk behaviors
-impulsive, easily-angered
how long does a manic episode typically last for diagnosis? what can trigger an episode?
-mood lasts for at least 7 days
-can be triggered by medication, stress, drug use, or spontaneous
Hypomanic Episode
less intense and shorter version of mania
Bipolar Disorder I
-at least one documented manic episode
-major depressive episodes common but not necessary for diagnosis
-diagnosis can be difficult or delayed
Bipolar Disorder II
-at least one major depressive episode & at least one episode of hypomania
Mood Disorder Treatment:
1) Diagnosis (w/ severity)
2) Discuss treatment modes w/ patient
3) Choose specific treatments
4) Follow-up/Monitoring (Most Important!)
SSRI's
-standard of care for depression treatment
-ease of dosing, minimal toxicity in overdose
-generally well-tolerated
-pt preferences, past responses, or family responses can be considered in selection
SNRI's
-trmt option that some clinicians consider first line with SSRIs
-NE receptor binding can help treat anxious distress or concentration issues associated with depression
-duloxetine also indicated for anxiety and neuropathic pain disorders, increasing utility in patients with comorbid issues
Course of Treatment Criteria:
-treatment course of 6 to 8 weeks is considered adequate to assess response
-after response is determined, may proceed with dose increase, augmentation, or change to new agent
-continuation of treatment for 9 months following adjustments as needed
Lithium Carbonate
***classic treatment for bipolar mania
-long term risk of renal impairment, thyroid impairment, tremor, etc.
-toxicity very possible and can cause disorientation, psychosis, and may be fatal; tight therapeutic window (requires blood monitoring for serum levels)
-can be used for antidepressant supplementation
Anxiety
-state of increased worry, fear, & concern, especially over future events
-S/S: increased HR/respiratory rate, agitation, tension
-may include avoidance behaviors and fears of "losing it" or "going crazy"
Panic Attack
-sudden, rapidly escalating onset of fear & anxiety, sometimes without provacation
-rapid HR, palpitations, sweating, dizziness, chest pain, hot or cold flashes, fear of death, depersonalization, etc.
Panic Disorder
-sudden & recurrent onset of panic attacks
-up to 25% experience nocturnal panic attacks
-fear of recurrence and increased anxiety over further attacks for at least a month after
-pt engages in avoidance behaviors to prevent future attacks
Generalized Anxiety Disorder (GAD)
-excessive, intrusive worries about everyday situations that causes significant stress and functional impairment
S/S: muscle tension, restlessness, insomnia, GI disturbance, headaches, fatigue, etc.
-may have episodes of increased anxiety that resemble panic attacks
Selective Mutism
refusal to speak due to increased anxiety, more common in children
post-traumatic stress disorder (PTSD)
Constellation of anxiety & depressive symptoms that originate as a response to an emotionally traumatic event; many cases resolve after 6 months; may be chronic in 1 out of 3 patients
Symptoms of PTSD:
flashbacks, nightmares, avoidance behavious, excessive worry, hyperviligence, insomnia, social isolation, sense of foreshortened future
Acute Stress Disorder
-onset of symptoms similar to PTSD in response to specific stressor
S/S: brief dissociation, doesn't exceed one month
Mixed Specifier:
during either a depressive or manic episode, exhibits at least 3 diagnostic criteria for the opposite mood are also present
Mood Spectrum:
mania> euthymia > depression
Agoraphobia specifier:
fear of marketplace
bipolar disorder diagnosis tips:
-rule out substance induced origin
-rule out origin due to medical conditions
-rule out other mental disorders
-note psychotic features specifier
-note anxious distress specifier
social anxiety disorder
debilitating anxiety in social situations and avoidance of socialization
specific phobia
avoidance of a specific situation or object that causes debilitating anxiety