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CD3
Associated Cell Types | Primary Biological Function | |
??? | All T Lymphocytes | Signal transduction subunit of T-Cell Receptor (TCR) complex |
CD4
??? | TH cells, Treg cells | Co-receptor for MHC Class II; target for HIV binding |
CD8
??? | Cytotoxic T (TC) cells | Co-receptor for MHC Class I molecules |
CD16
??? | NK cells, Neutrophils, Macrophages | FcγRIII receptor; mediates Antibody-Dependent Cellular Cytotoxicity (ADCC) |
CD20
??? | B cells (Late pre-B to mature) | Regulates B-cell activation, proliferation, and differentiation |
CD21
??? | B cells, Follicular Dendritic Cells | Receptor for complement breakdown product C3d; Epstein-Barr Virus (EBV) & C3d receptor |
CD56
??? | NK cells | Adhesion molecule; primary phenotypic marker for human NK cells |
CD19
??? | B cells, Follicular Dendritic Cells | Part of B-cell co-receptor complex; regulates B-cell activation and development |